SCHEMBL18780698

SCHEMBL18780698

Cc1ccc(P(=O)(c2ccc(C)cc2)c2ccc(-c3cccc(-c4ccc(P(=O)(c5ccc(C)cc5)c5ccc(C)cc5)cc4)c3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN5 P54829 1/20 0.51
HPGD P15428 2/20 0.46
DHODH Q02127 1/20 0.46
LMNA P02545 1/20 0.45
TSHR P16473 1/20 0.45
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
ESR1 P03372 1/20 0.41
GAA P10253 3/20 0.41
CA12 O43570 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
MCL1 Q07820 1/20 0.39
MAPT P10636 6/20 0.39
ALKBH3 Q96Q83 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26377046 0.94 PTPN5 (0.51) PTPN5HPGDDHODHLMNATSHR
SCHEMBL18780701 0.87 HPGD (0.59) PTPN5HPGDLMNATSHRMEN1
SCHEMBL18780696 0.86 HSD17B1 (0.43) PTPN5HPGDDHODHLMNAMEN1
SCHEMBL18780695 0.85 KMO (0.48) PTPN5LMNAMEN1KMT2AESR1
SCHEMBL9927317 0.85 KMO (0.48) PTPN5LMNAMEN1KMT2AESR1
SCHEMBL29892442 0.84 MEN1 (0.55) PTPN5HPGDDHODHMEN1KMT2A
SCHEMBL4402340 0.83 HPGD (0.56) PTPN5HPGDLMNATSHRMEN1
SCHEMBL17451971 0.83 LMNA (0.47) PTPN5LMNAMEN1KMT2AESR1
SCHEMBL5435185 0.82 HPGD (0.65) HPGDLMNATSHRMEN1KMT2A
SCHEMBL262688 0.82 HPGD (0.65) HPGDLMNATSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9857705-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2018-01-02 US disclosed
US-20170115582-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-04-27 US disclosed
US-20170115582-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-04-27 US disclosed