Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 4/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855608 | 0.83 | DAO (0.38) | DAOFDPSNOS1NOS3TLR8 | |
| SCHEMBL21996409 | 0.80 | FDPS (0.38) | DAOFDPSNOS1NOS3THRB | |
| SCHEMBL13715227 | 0.80 | DAO (0.36) | DAOFDPSNOS1NOS3TLR8 | |
| SCHEMBL16861331 | 0.79 | FDPS (0.36) | DAOFDPSNOS1NOS3TLR8 | |
| SCHEMBL28667189 | 0.76 | LMNA (0.37) | DAOFDPSTHRBTSHRLMNA | |
| SCHEMBL19992033 | 0.75 | LMNA (0.38) | DAOFDPSTHRBTSHRKDM4E | |
| SCHEMBL5713341 | 0.75 | DAO (0.50) | DAOFDPSNOS1NOS3THRB | |
| SCHEMBL33257 | 0.73 | — | — | |
| SCHEMBL23920175 | 0.73 | DAO (0.37) | DAOFDPSTLR8TLR7THRB | |
| SCHEMBL19049543 | 0.72 | TLR8 (0.34) | DAOFDPSTLR8TLR7THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017069270-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | 大正製薬株式会社 | 2017-04-27 | — | — | WO | disclosed |