Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.50 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187924 | 0.91 | TK1 (0.41) | TK1POLB | |
| SCHEMBL9083809 | 0.91 | POLA1 (0.50) | TK1POLB | |
| SCHEMBL187829 | 0.90 | TK1 (0.62) | TK1TYMSPOLB | |
| SCHEMBL187972 | 0.86 | TK1 (0.50) | TK1TYMSPOLB | |
| SCHEMBL9083114 | 0.84 | TK1 (0.51) | TK1POLB | |
| SCHEMBL186844 | 0.81 | TK1 (0.51) | TK1POLB | |
| SCHEMBL8815106 | 0.81 | POLB (0.60) | TK1POLB | |
| SCHEMBL187710 | 0.78 | TK1 (0.41) | TK1POLB | |
| SCHEMBL30564142 | 0.78 | TK1 (0.57) | TK1TYMSPOLB | |
| Phosphoric Acid SCHEMBL1445017 | 0.76 | TK1 (0.53) | TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402357-A1 | Analogs of 2',3'-dideoxy-3'-fluorothymidine 5'-monophosphate (FLTMP) for treatment human immunodeficiency virus (HIV), their application and pharmaceutically acceptable form of drug | Instytut Biochemii I Biofizyki Pan (PL) | 2012-01-04 | — | — | EP | claimed |
| EP-2402357-B1 | Analogs of 2',3'-dideoxy-3'-fluorothymidine 5'-monophosphate (FLTMP) for use in the treatment of infections caused by human HIV-1 strains | INST BIOCHEMII I BIOFIZYKI PAN (PL) | 2015-10-14 | — | — | EP | disclosed |
| EP-2402357-A1 | Analogs of 2',3'-dideoxy-3'-fluorothymidine 5'-monophosphate (FLTMP) for treatment human immunodeficiency virus (HIV), their application and pharmaceutically acceptable form of drug | Instytut Biochemii I Biofizyki Pan (PL) | 2012-01-04 | — | — | EP | disclosed |
| EP-2402357-A1 | Analogs of 2',3'-dideoxy-3'-fluorothymidine 5'-monophosphate (FLTMP) for treatment human immunodeficiency virus (HIV), their application and pharmaceutically acceptable form of drug | Instytut Biochemii I Biofizyki Pan (PL) | 2012-01-04 | — | — | EP | disclosed |