Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.45 |
| ▸ | POLD1 | P28340 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187829 | 0.85 | TK1 (0.62) | TK1POLBTYMSPOLA1POLD1 | |
| SCHEMBL186844 | 0.78 | TK1 (0.51) | TK1POLBPOLA1POLD1 | |
| SCHEMBL4523006 | 0.78 | POLB (0.55) | TK1POLBPOLA1POLD1 | |
| SCHEMBL187972 | 0.78 | TK1 (0.50) | TK1POLBTYMSPOLA1POLD1 | |
| SCHEMBL187841 | 0.78 | TK1 (0.50) | TK1POLBTYMS | |
| SCHEMBL8815106 | 0.77 | POLB (0.60) | TK1POLBPOLA1POLD1 | |
| SCHEMBL23440065 | 0.76 | TK1 (0.67) | TK1POLBTYMSPOLA1POLD1 | |
| SCHEMBL28774920 | 0.76 | TK1 (0.67) | TK1POLBTYMSPOLA1POLD1 | |
| SCHEMBL26757571 | 0.76 | TK1 (0.67) | TK1POLBTYMSPOLA1POLD1 | |
| SCHEMBL8883 | 0.76 | TK1 (0.67) | TK1POLBTYMSPOLA1POLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499659-A1 | NUCLEOSIDES AND NUCLEOTIDES WITH 3' VINYL BLOCKING GROUP USEFUL IN SEQUENCING BY SYNTHESIS | ILLUMINA, INC. (US) | 2025-02-05 | — | — | EP | disclosed |
| US-20230332197-A1 | NUCLEOSIDES AND NUCLEOTIDES WITH 3' VINYL BLOCKING GROUP | ILLUMINA, INC. | 2023-10-19 | — | — | US | disclosed |
| WO-2023192900-A1 | NUCLEOSIDES AND NUCLEOTIDES WITH 3' VINYL BLOCKING GROUP USEFUL IN SEQUENCING BY SYNTHESIS | ILLUMINA SINGAPORE PTE. LTD. (SG) | 2023-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230332197-A1 | NUCLEOSIDES AND NUCLEOTIDES WITH 3' VINYL BLOCKING GROUP | NT5C3B, NSUN2, DUT | TK1 132/4885POLB 42/4885TYMS 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.