Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28696476 | 0.85 | ALDH1A1 (0.60) | MAPTGAAALDH1A1KDM4EHPGD | |
| SCHEMBL593745 | 0.80 | MAPT (0.50) | MAPTGAAALDH1A1KDM4EHPGD | |
| SCHEMBL4175858 | 0.80 | KDM4E (0.56) | MAPTGAAALDH1A1KDM4EHPGD | |
| SCHEMBL28659478 | 0.79 | FDPS (0.46) | MAPTGAAALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL28144703 | 0.78 | MAPT (0.48) | MAPTGAAALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL9151636 | 0.78 | KDM4E (0.54) | MAPTGAAALDH1A1KDM4EHPGD | |
| SCHEMBL72851 | 0.77 | AKR1B1 (0.61) | MAPTGAAKDM4EHPGDTSHR | |
| SCHEMBL5164226 | 0.77 | FDPS (0.44) | MAPTGAAALDH1A1KDM4EHPGD | |
| SCHEMBL1039164 | 0.77 | FDPS (0.48) | MAPTGAAALDH1A1KDM4EHPGD | |
| SCHEMBL10572853 | 0.77 | MAPT (0.52) | MAPTGAAALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10703746-B2 | Mutant IDH1 inhibitors useful for treating cancer | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2020-07-07 | — | — | US | disclosed |
| US-9822205-B2 | Deoxybenzoin-derived anti-flammable polymers | UNIVERSITY OF MASSACHUSETTS (US) | 2017-11-21 | — | — | US | disclosed |
| US-9340635-B2 | Deoxybenzoin-derived anti-flammable polymers | UNIVERSITY OF MASSACHUSETTS (US) | 2016-05-17 | — | — | US | disclosed |
| US-20160009854-A1 | DEOXYBENZOIN-DERIVED ANTI-FLAMMABLE POLYMERS | UNIVERSITY OF MASSACHUSETTS | 2016-01-14 | — | — | US | disclosed |
| US-20160009841-A1 | DEOXYBENZOIN-DERIVED ANTI-FLAMMABLE POLYMERS | UNIVERSITY OF MASSACHUSETTS | 2016-01-14 | — | — | US | disclosed |
| US-9175131-B2 | Deoxybenzoin-derived anti-flammable polymers | UNIVERSITY OF MASSACHUSETTS (US) | 2015-11-03 | — | — | US | disclosed |
| US-20130102754-A1 | DEOXYBENZOIN-DERIVED ANTI-FLAMMABLE POLYMERS | UNIVERSITY OF MASSACHUSETTS (US) | 2013-04-25 | — | — | US | disclosed |
| US-8314202-B2 | Deoxybenzoin-derived anti-flammable polymers | UNIVERSITY OF MASSACHUSETTS (US) | 2012-11-20 | — | — | US | disclosed |
| US-20110112241-A1 | DEOXYBENZOIN-DERIVED ANTI-FLAMMABLE POLYMERS | UNIVERSITY OF MASSACHUSETTS | 2011-05-12 | — | — | US | disclosed |
| WO-2009123969-A2 | DEOXYBENZOIN-DERIVED ANTI-FLAMMABLE POLYMERS | UNIVERSITY OF MASSACHUSETTS (US) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10703746-B2 | Mutant IDH1 inhibitors useful for treating cancer | IDH1, IDH3B, IDH3A | MAPT 4568/4885GAA 141/4885ALDH1A1 417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.