Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | PDE4A | P27815 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.64 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.64 |
| ▸ | JAK3 | P52333 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31206327 | 1.00 | MAPT (0.66) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5471126 | 0.91 | RAB9A (0.65) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5640255 | 0.87 | KMT2A (0.78) | MAPTKMT2ARAB9AMEN1GRIK1 | |
| SCHEMBL10710484 | 0.86 | MEN1 (0.77) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1514604 | 0.85 | MAPT (0.62) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31206271 | 0.85 | KMT2A (0.74) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL21858396 | 0.85 | KMT2A (0.74) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1878682 | 0.83 | MEN1 (0.65) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL725553 | 0.83 | IDH1 (0.69) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11048619 | 0.82 | MEN1 (0.76) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3000459-B1 | ANTIPERSPIRANT COMPOSITIONS | JOHNSON & JOHNSON CONSUMER INC (US) | 2019-07-17 | — | — | EP | claimed |
| EP-2875141-A1 | ANTIMICROBIAL AGENTS | Bedoukian Research, Inc. (US) | 2015-05-27 | — | — | EP | claimed |
| US-20150125402-A1 | ANTIMICROBIAL AGENTS | BEDOUKIAN RESEARCH, INC. | 2015-05-07 | — | — | US | claimed |
| WO-2014014490-A1 | ANTIMICROBIAL AGENTS | BEDOUKIAN RESEARCH, INC. (US) | 2014-01-23 | — | — | WO | claimed |
| EP-0938288-B1 | PERFUMED PRODUCTS | QUEST INT (NL) | 2002-03-27 | — | — | EP | claimed |
| US-6241979-B1 | Perfumed products containing a mixture of perfume materials having antibacterial properties | QUEST INTERNATIONAL B.V. (NL) | 2001-06-05 | — | — | US | claimed |
| EP-0938288-A1 | PERFUMED PRODUCTS | QUEST INTERNATIONAL B.V. (NL) | 1999-09-01 | — | — | EP | claimed |
| WO-1998016194-A1 | PERFUMED PRODUCTS | QUEST INTERNATIONAL B.V. (NL) | 1998-04-23 | — | — | WO | claimed |
| US-4322308-A | Detergent product containing deodorant compositions | LEVER BROTHERS COMPANY (US) | 1982-03-30 | — | — | US | claimed |
| US-20210380547-A1 | UREA DERIVATIVES FOR TREATING AND/OR PREVENTING CANCER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-12-09 | — | — | US | disclosed |
| WO-2020079184-A2 | UREA DERIVATIVES FOR TREATING AND/OR PREVENTING CANCER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-04-23 | — | — | WO | disclosed |
| US-9932300-B2 | N,N′-diarylurea compounds and N,N′-diarylthiourea compounds as inhibitors of translation initiation | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-04-03 | — | — | US | disclosed |
| US-9932300-B2 | N,N′-diarylurea compounds and N,N′-diarylthiourea compounds as inhibitors of translation initiation | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-04-03 | — | — | US | disclosed |
| US-20160318857-A1 | N,N'-Diarylurea Compounds and N,N'-Diarylthiourea Compounds as Inhibitors of Translation Initiation | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2016-11-03 | — | — | US | disclosed |
| EP-0478327-A1 | Method for thickening metal-containing products using DMDAAC/acrylic acid-type polymers | CALGON CORPORATION (US) | 1992-04-01 | — | — | EP | disclosed |
| US-4684728-A | Solubilizing biologically active compounds with reactive hydrogen atoms | BAYER AKTIENGESELLSCHAFT (DE) | 1987-08-04 | — | — | US | disclosed |
| EP-0084708-B1 | POLYSACCHARIDE OR PROTEIN ARTICLES WITH INCLUDED NON-AQUEOUS LIQUID | UNILEVER PLC (GB) | 1986-01-22 | — | — | EP | disclosed |
| US-4471871-A | Packaged dry-to-the-touch article and method of packaging the article | LEVER BROTHERS COMPANY (US) | 1984-09-18 | — | — | US | disclosed |
| EP-0084708-A1 | Polysaccharide or protein articles with included non-aqueous liquid | UNILEVER PLC (GB) | 1983-08-03 | — | — | EP | disclosed |
| US-3969259-A | 2,4,4'-TRICHLORO-2'-HYDROXY DIPHENYL ETHER | LEVER BROTHERS COMPANY (US) | 1976-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318857-A1 | N,N'-Diarylurea Compounds and N,N'-Diarylthiourea Compounds as Inhibitors of Translation Initiation | NSUN2, EIF2AK2, RNGTT | MAPT 1631/4885KMT2A 761/4885RAB9A 2490/4885 |
| US-20210380547-A1 | UREA DERIVATIVES FOR TREATING AND/OR PREVENTING CANCER | CXCR1, CXCR2, CXCR6 | MAPT 3890/4885KMT2A 3423/4885RAB9A 1386/4885 |
| US-20150125402-A1 | ANTIMICROBIAL AGENTS | SOD1, ERG28, ARG1 | MAPT 4149/4885KMT2A 4468/4885RAB9A 4290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.