Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.61 |
| ▸ | DHCR7 | Q9UBM7 | 2/20 | 0.61 |
| ▸ | S100A4 | P26447 | 5/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 4/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 8/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | THRB | P10828 | 7/20 | 0.60 |
| ▸ | BLM | P54132 | 6/20 | 0.60 |
| ▸ | TOP2A | P11388 | 5/20 | 0.60 |
| ▸ | RECQL | P46063 | 5/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | BRCA1 | P38398 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17345374 | 1.00 | EBP (0.61) | EBPDHCR7S100A4PAX8HSP90AA1 | |
| SCHEMBL18821853 | 1.00 | EBP (0.61) | EBPDHCR7S100A4PAX8HSP90AA1 | |
| SCHEMBL18787089 | 1.00 | EBP (0.61) | EBPDHCR7S100A4PAX8HSP90AA1 | |
| SCHEMBL28667008 | 1.00 | EBP (0.61) | EBPDHCR7S100A4PAX8HSP90AA1 | |
| SCHEMBL19231138 | 1.00 | EBP (0.61) | EBPDHCR7S100A4PAX8HSP90AA1 | |
| SCHEMBL19565420 | 1.00 | EBP (0.61) | EBPDHCR7S100A4PAX8HSP90AA1 | |
| SCHEMBL28676530 | 1.00 | EBP (0.61) | EBPDHCR7S100A4PAX8HSP90AA1 | |
| SCHEMBL18806491 | 1.00 | EBP (0.61) | EBPDHCR7S100A4PAX8HSP90AA1 | |
| SCHEMBL19231139 | 1.00 | EBP (0.61) | EBPDHCR7S100A4PAX8HSP90AA1 | |
| SCHEMBL19565417 | 0.96 | EBP (0.55) | EBPDHCR7S100A4PAX8HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250108031-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | BACH BIOSCIENCES, LLC | 2025-04-03 | — | — | US | disclosed |
| US-20240398842-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | BACH BIOSCIENCES, LLC | 2024-12-05 | — | — | US | disclosed |
| US-12121505-B2 | Fap-activated therapeutic agents, and uses related thereto | BACH BIOSCIENCES, LLC (US) | 2024-10-22 | — | — | US | disclosed |
| US-12053450-B2 | FAP-activated therapeutic agents, and uses related thereto | BACH BIOSCIENCES, LLC (US) | 2024-08-06 | — | — | US | disclosed |
| US-12023316-B2 | FAP-activated therapeutic agents, and uses related thereto | BACH BIOSCIENCES, LLC (US) | 2024-07-02 | — | — | US | disclosed |
| US-11925655-B2 | FAP-activated therapeutic agents, and uses related thereto | BACH BIOSCIENCES, LLC (US) | 2024-03-12 | — | — | US | disclosed |
| EP-4299134-A2 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | Bach Biosciences, LLC (US) | 2024-01-03 | — | — | EP | disclosed |
| EP-3154594-B1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | BACH BIOSCIENCES LLC (US) | 2023-07-19 | — | — | EP | disclosed |
| US-20220296621-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | BACH BIOSCIENCES, LLC | 2022-09-22 | — | — | US | disclosed |
| US-20220087971-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | BACH BIOSCIENCES, LLC | 2022-03-24 | — | — | US | disclosed |
| US-11033525-B2 | Fap-activated therapeutic agents, and uses related thereto | BACH BIOSCIENCES, LLC (US) | 2021-06-15 | — | — | US | disclosed |
| US-20200297745-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | BACH BIOSCIENCES, LLC | 2020-09-24 | — | — | US | disclosed |
| US-10709722-B2 | FAP-activated therapeutic agents, and uses related thereto | BACH BIOSCIENCES, LLC (US) | 2020-07-14 | — | — | US | disclosed |
| US-20190275064-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | TRUSTEES OF TUFTS COLLEGE | 2019-09-12 | — | — | US | disclosed |
| US-10245248-B2 | FAP-activated therapeutic agents, and uses related thereto | BACH BIOSCIENCES, LLC (US) | 2019-04-02 | — | — | US | disclosed |
| US-10117887-B2 | FAP-activated therapeutic agents, and uses related thereto | BACH BIOSCIENCES, LLC (US) | 2018-11-06 | — | — | US | disclosed |
| US-20170319609-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | BACH BIOSCIENCES, LLC | 2017-11-09 | — | — | US | disclosed |
| US-9737556-B2 | FAP-activated therapeutic agents, and uses related thereto | TRUSTEES OF TUFTS COLLEGE (US) | 2017-08-22 | — | — | US | disclosed |
| US-20170128476-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | BACH BIOSCIENCES, LLC | 2017-05-11 | — | — | US | disclosed |
| US-20170119901-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | BACH BIOSCIENCES, LLC | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (17 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12121505-B2 | Fap-activated therapeutic agents, and uses related thereto | FAP, FIBP, GOT1 | EBP 3510/4885DHCR7 3123/4885S100A4 1115/4885 |
| US-11033525-B2 | Fap-activated therapeutic agents, and uses related thereto | FAP, FIBP, GOT1 | EBP 3510/4885DHCR7 3123/4885S100A4 1115/4885 |
| US-20250108031-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | FAP, FIBP, GOT1 | EBP 3510/4885DHCR7 3123/4885S100A4 1115/4885 |
| US-20200297745-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | FAP, FIBP, GOT1 | EBP 3103/4885DHCR7 2487/4885S100A4 1982/4885 |
| US-20170128476-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | FAP, FIBP, GOT1 | EBP 2814/4885DHCR7 2404/4885S100A4 1836/4885 |
| US-10709722-B2 | FAP-activated therapeutic agents, and uses related thereto | FAP, FIBP, GOT1 | EBP 3103/4885DHCR7 2487/4885S100A4 1982/4885 |
| US-12023316-B2 | FAP-activated therapeutic agents, and uses related thereto | FAP, FIBP, GOT1 | EBP 3510/4885DHCR7 3123/4885S100A4 1115/4885 |
| US-10117887-B2 | FAP-activated therapeutic agents, and uses related thereto | FAP, FIBP, GOT1 | EBP 2814/4885DHCR7 2404/4885S100A4 1836/4885 |
| US-20220296621-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | FAP, FIBP, GOT1 | EBP 3181/4885DHCR7 2536/4885S100A4 2079/4885 |
| US-10245248-B2 | FAP-activated therapeutic agents, and uses related thereto | FAP, FIBP, FAH | EBP 3802/4885DHCR7 3662/4885S100A4 1791/4885 |
| US-12053450-B2 | FAP-activated therapeutic agents, and uses related thereto | FAP, FIBP, GOT1 | EBP 3510/4885DHCR7 3123/4885S100A4 1115/4885 |
| US-11925655-B2 | FAP-activated therapeutic agents, and uses related thereto | FAP, FIBP, GOT1 | EBP 3181/4885DHCR7 2536/4885S100A4 2079/4885 |
| US-20190275064-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | FAP, FIBP, GOT1 | EBP 3103/4885DHCR7 2487/4885S100A4 1982/4885 |
| US-20240398842-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | FAP, FIBP, GOT1 | EBP 3103/4885DHCR7 2487/4885S100A4 1982/4885 |
| US-20170119901-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | FAP, FIBP, FAH | EBP 3802/4885DHCR7 3662/4885S100A4 1791/4885 |
| US-20170319609-A1 | FAP-Activated Therapeutic Agents, and Uses Related Thereto | FAP, FIBP, GOT1 | EBP 2814/4885DHCR7 2404/4885S100A4 1836/4885 |
| US-20220087971-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | FAP, FIBP, GOT1 | EBP 3510/4885DHCR7 3123/4885S100A4 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.