SCHEMBL18790076

SCHEMBL18790076

CSc1nc(S)nc(SC)n1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HSP90AB1 P08238 2/20 0.39
HSP90AA1 P07900 2/20 0.31
MAPK1 P28482 2/20 0.31
DCUN1D1 Q96GG9 1/20 0.31
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13009780 0.94 HSP90AB1 (0.39) HSP90AB1HSP90AA1MAPK1DCUN1D1PKM
SCHEMBL7537282 0.83 HSP90AB1 (0.48) HSP90AB1HSP90AA1MAPK1PKM
SCHEMBL23432491 0.80 ALPL (0.32) HSP90AB1
SCHEMBL20734761 0.78 MAPT (0.32) HSP90AB1
SCHEMBL22680278 0.77 TSHR (0.31)
SCHEMBL24348447 0.77 KDM4E (0.37) HSP90AB1HSP90AA1
SCHEMBL22679906 0.74 GPR84 (0.36) HSP90AA1
SCHEMBL24348446 0.74 MAPK1 (0.38) HSP90AB1HSP90AA1MAPK1DCUN1D1
SCHEMBL9243430 0.73 POLB (0.43) HSP90AB1HSP90AA1MAPK1PKM
SCHEMBL11679877 0.72 HSP90AA1 (0.64) HSP90AB1HSP90AA1MAPK1DCUN1D1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814482-B2 Triazine ring-containing polymer, and thermoplastic article and optical part including same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-11-14 US disclosed
EP-3105040-B1 COMPOSITION AND METHOD FOR ADDITIVE MANUFACTURING OF AN OBJECT STRATASYS LTD (IL) 2023-10-18 EP disclosed
EP-3414275-B1 ORGANOMETALLIC COMPLEXES OF SEQUENTIAL TETRADENTATE MONOANIONIC LIGANDS AND USES THEREOF IN RING OPENING POLYMERIZATION OF CYCLIC ESTERS UNIV RAMOT (IL) 2023-07-05 EP disclosed
EP-3478742-B1 BLOCK COPOLYMERS OF CYCLIC ESTERS AND PROCESSES FOR PREPARING SAME UNIV RAMOT (IL) 2022-11-02 EP disclosed
US-20210163682-A1 TRIAZINE RING-CONTAINING POLYMER, AND THERMOPLASTIC ARTICLE AND OPTICAL PART INCLUDING SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-06-03 US disclosed
WO-2017134676-A1 DIGITALLY-CONTROLLED THREE-DIMENSIONAL PRINTING USING RING- OPENING METATHESIS POLYMERIZATION STRATASYS LTD. (IL) 2017-08-10 WO disclosed
WO-2017134673-A1 THREE-DIMENSIONAL PRINTING COMBINING RING-OPENING METATHESIS POLYMERIZATION AND FREE RADICAL POLYMERIZATION STRATASYS LTD. (IL) 2017-08-10 WO disclosed
WO-2017068590-A1 THREE-DIMENSIONAL INKJET PRINTING USING DICYCLOPENTADIENE COMPOUNDS POLYMERIZABLE BY RING-OPENING METATHESIS POLYMERIZATION STRATASYS LTD. (IL) 2017-04-27 WO disclosed