Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 5/20 | 0.51 |
| ▸ | DCUN1D1 | Q96GG9 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14960484 | 1.00 | UBE2M (0.51) | UBE2MDCUN1D1KDM4EMEN1KMT2A | |
| SCHEMBL13326991 | 1.00 | UBE2M (0.51) | UBE2MDCUN1D1KDM4EMEN1KMT2A | |
| SCHEMBL29726754 | 0.95 | DCUN1D1 (0.48) | UBE2MDCUN1D1KDM4EMEN1KMT2A | |
| SCHEMBL18790116 | 0.95 | DCUN1D1 (0.48) | UBE2MDCUN1D1KDM4EMEN1KMT2A | |
| SCHEMBL16280646 | 0.95 | DCUN1D1 (0.48) | UBE2MDCUN1D1KDM4EMEN1KMT2A | |
| SCHEMBL18609701 | 0.95 | DCUN1D1 (0.48) | UBE2MDCUN1D1KDM4EMEN1KMT2A | |
| SCHEMBL12160761 | 0.95 | DCUN1D1 (0.48) | UBE2MDCUN1D1KDM4EMEN1KMT2A | |
| SCHEMBL2579735 | 0.95 | DCUN1D1 (0.48) | UBE2MDCUN1D1KDM4EMEN1KMT2A | |
| SCHEMBL12176191 | 0.92 | ALDH1A1 (0.43) | UBE2MDCUN1D1ALDH1A1EPHX2LMNA | |
| SCHEMBL18532606 | 0.92 | ALDH1A1 (0.43) | UBE2MDCUN1D1ALDH1A1EPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015504-A1 | C5AR ANTAGONISTS | ChemoCentryx, Inc. (US) | 2022-06-22 | — | — | EP | disclosed |
| EP-3508477-A1 | C5AR ANTAGONISTS | ChemoCentryx, Inc. (US) | 2019-07-10 | — | — | EP | disclosed |
| US-20170114017-A1 | C5AR ANTAGONISTS | CHEMOCENTRYX, INC. | 2017-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114017-A1 | C5AR ANTAGONISTS | C5AR1, C5AR2, C3AR1 | UBE2M 4268/4885DCUN1D1 1926/4885KDM4E 4012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.