Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.48 |
| ▸ | PIM3 | Q86V86 | 5/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 2/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18790689 | 0.88 | CYP11B2 (0.44) | PIM2PIM3CYP11B2RAD52PIM1 | |
| SCHEMBL18790696 | 0.86 | CYP11B2 (0.61) | PIM2PIM3CYP11B2RAD52PIM1 | |
| SCHEMBL18790687 | 0.84 | CYP11B2 (0.49) | PIM2PIM3CYP11B2RAD52PIM1 | |
| SCHEMBL20514041 | 0.81 | CYP11B2 (0.68) | CYP11B2LRRK2DYRK1A | |
| SCHEMBL18790686 | 0.80 | PIM2 (0.57) | PIM2PIM3PIM1 | |
| SCHEMBL20514060 | 0.79 | PIM2 (0.42) | PIM2PIM3CYP11B2RAD52PIM1 | |
| SCHEMBL17207634 | 0.76 | CYP11B2 (0.68) | CYP11B2 | |
| SCHEMBL20514040 | 0.73 | CYP11B2 (0.43) | PIM2PIM3CYP11B2RAD52PIM1 | |
| SCHEMBL18790985 | 0.73 | CYP11B2 (0.48) | PIM2CYP11B2RAD52PIM1CSNK2A1 | |
| SCHEMBL22236803 | 0.71 | ROCK2 (0.56) | PIM2PIM3PIM1CDK8DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381904-B1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2021-07-28 | — | — | EP | disclosed |
| WO-2017069226-A1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | 田辺三菱製薬株式会社 | 2017-04-27 | — | — | WO | disclosed |