Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 6/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 7/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 5/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20514040 | 0.80 | CYP11B2 (0.43) | PIM2CYP11B2PIM1CSNK2A1PIM3 | |
| SCHEMBL18790685 | 0.79 | PIM2 (0.48) | PIM2CYP11B2PIM1CSNK2A1PIM3 | |
| SCHEMBL18790696 | 0.79 | CYP11B2 (0.61) | PIM2CYP11B2PIM1CSNK2A1PIM3 | |
| SCHEMBL18790687 | 0.76 | CYP11B2 (0.49) | PIM2CYP11B2PIM1CSNK2A1PIM3 | |
| SCHEMBL18790686 | 0.76 | PIM2 (0.57) | PIM2PIM1PIM3 | |
| SCHEMBL18790689 | 0.76 | CYP11B2 (0.44) | PIM2CYP11B2PIM1CSNK2A1PIM3 | |
| SCHEMBL18489986 | 0.71 | CYP11B2 (0.51) | CYP11B2 | |
| SCHEMBL28544147 | 0.71 | CYP11B2 (0.51) | CYP11B2 | |
| SCHEMBL20514041 | 0.70 | CYP11B2 (0.68) | CYP11B2GSK3BDYRK1A | |
| SCHEMBL22236803 | 0.68 | ROCK2 (0.56) | PIM2PIM1PIM3CDK8DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381904-B1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2021-07-28 | — | — | EP | claimed |
| US-10717731-B2 | Nitrogen-containing aromatic heterocyclic compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2020-07-21 | — | — | US | disclosed |
| US-20180312503-A1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2018-11-01 | — | — | US | disclosed |
| EP-3381904-A1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2018-10-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10717731-B2 | Nitrogen-containing aromatic heterocyclic compound | REN, NR3C2, NR5A1 | PIM2 4330/4885CYP11B2 8/4885TRPV1 3720/4885 |
| US-20180312503-A1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | REN, NR3C2, NR5A1 | PIM2 4265/4885CYP11B2 8/4885TRPV1 3416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.