Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18790697 | 0.91 | CYP11B2 (0.69) | CYP11B2KMT2AMEN1POLBCYP11B1 | |
| SCHEMBL18790705 | 0.87 | CYP11B2 (0.65) | CYP11B2KMT2AMEN1POLBCYP11B1 | |
| SCHEMBL18791038 | 0.86 | CYP11B2 (0.64) | CYP11B2KMT2AMEN1POLBCYP11B1 | |
| SCHEMBL18790694 | 0.84 | CYP11B2 (0.61) | CYP11B2KMT2AMEN1POLBCYP11B1 | |
| SCHEMBL18791026 | 0.78 | GAA (0.53) | CYP11B2CYP11B1DRD2DRD4DRD3 | |
| SCHEMBL18791106 | 0.77 | CYP11B2 (0.53) | CYP11B2KMT2AMEN1CYP11B1MAPT | |
| SCHEMBL18791036 | 0.76 | HTR7 (0.56) | CYP11B2KMT2AMEN1 | |
| SCHEMBL18790708 | 0.76 | CYP11B2 (0.58) | CYP11B2CYP11B1GRIN2B | |
| SCHEMBL18791104 | 0.75 | CYP11B2 (0.51) | CYP11B2KMT2AMEN1CYP11B1MAPT | |
| SCHEMBL3436278 | 0.71 | LMNA (0.55) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381904-B1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2021-07-28 | — | — | EP | disclosed |
| WO-2017069226-A1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | 田辺三菱製薬株式会社 | 2017-04-27 | — | — | WO | disclosed |