Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 19/20 | 0.72 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18790704 | 0.77 | SLC6A9 (0.47) | CYP11B2CYP11B1 | |
| SCHEMBL20513563 | 0.74 | CYP11B2 (0.71) | CYP11B2CYP11B1 | |
| SCHEMBL20513565 | 0.74 | CYP11B2 (0.71) | CYP11B2CYP11B1 | |
| SCHEMBL18790710 | 0.71 | CYP11B2 (0.54) | CYP11B2 | |
| SCHEMBL20546955 | 0.69 | CYP11B2 (0.56) | CYP11B2GRIN1GRIN2B | |
| SCHEMBL20513745 | 0.69 | CYP11B2 (0.56) | CYP11B2GRIN1GRIN2B | |
| SCHEMBL18791032 | 0.69 | CYP11B2 (0.48) | CYP11B2CYP11B1 | |
| SCHEMBL18791093 | 0.68 | CYP11B2 (0.66) | CYP11B2CYP11B1GRIN2B | |
| SCHEMBL22236794 | 0.68 | USP30 (0.46) | CYP11B2CYP11B1 | |
| SCHEMBL18790707 | 0.67 | CYP11B2 (0.50) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381904-B1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2021-07-28 | — | — | EP | disclosed |
| US-10717731-B2 | Nitrogen-containing aromatic heterocyclic compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2020-07-21 | — | — | US | disclosed |
| WO-2017069226-A1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | 田辺三菱製薬株式会社 | 2017-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10717731-B2 | Nitrogen-containing aromatic heterocyclic compound | REN, NR3C2, NR5A1 | CYP11B2 8/4885CYP11B1 6/4885GRIN1 1262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.