Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22309044 | 0.94 | CES1 (0.41) | CA2CES1TRPV1 | |
| SCHEMBL21784946 | 0.92 | NPC1 (0.45) | MAPTNPC1RAB9ACA2CES1 | |
| SCHEMBL18790795 | 0.85 | CES1 (0.54) | MAPTNPC1RAB9ACES1ALDH1A1 | |
| SCHEMBL18790460 | 0.83 | CES1 (0.56) | MAPTNPC1RAB9ACA2CES1 | |
| SCHEMBL21784939 | 0.77 | ALDH1A1 (0.50) | MAPTNPC1RAB9ACA2CES1 | |
| SCHEMBL18790471 | 0.76 | CES1 (0.62) | MAPTCA2CES1TRPV1ALDH1A1 | |
| SCHEMBL11482921 | 0.76 | CES1 (0.50) | MAPTNPC1RAB9ACES1ALDH1A1 | |
| SCHEMBL11086692 | 0.76 | GSK3B (0.43) | MAPTNPC1RAB9ACA2CES1 | |
| SCHEMBL9065321 | 0.74 | CES1 (0.66) | MAPTNPC1CES1ALDH1A1SMN1; SMN2 | |
| SCHEMBL36702 | 0.74 | CES1 (0.66) | MAPTNPC1CES1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017067634-A1 | BENZIL MONOKETALAND USE THEREOF | MERCK PATENT GMBH (DE) | 2017-04-27 | — | — | WO | disclosed |