Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18790794 | 0.92 | MAPT (0.40) | NPC1RAB9AMAPTCA2CES1 | |
| SCHEMBL18790795 | 0.92 | CES1 (0.54) | NPC1RAB9AMAPTCES1ALDH1A1 | |
| SCHEMBL22309044 | 0.85 | CES1 (0.41) | CA2CES1GSK3B | |
| SCHEMBL21784939 | 0.83 | ALDH1A1 (0.50) | NPC1RAB9AMAPTCA2CES1 | |
| SCHEMBL11482921 | 0.82 | CES1 (0.50) | NPC1RAB9AMAPTCES1ALDH1A1 | |
| SCHEMBL11086692 | 0.82 | GSK3B (0.43) | NPC1RAB9AMAPTCA2CES1 | |
| SCHEMBL36702 | 0.81 | CES1 (0.66) | NPC1MAPTCES1ALDH1A1LMNA | |
| SCHEMBL9065321 | 0.81 | CES1 (0.66) | NPC1MAPTCES1ALDH1A1LMNA | |
| SCHEMBL9800584 | 0.80 | CES1 (0.65) | NPC1RAB9AMAPTCA2CES1 | |
| SCHEMBL10714002 | 0.79 | CA2 (0.46) | NPC1RAB9AMAPTCA2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071617-A1 | LIQUID CRYSTAL DISPLAY ELEMENT | DIC CORPORATION (JP) | 2020-03-05 | — | — | US | disclosed |