SCHEMBL18791107 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	GPR119	Q8TDV5	15/20	0.49

▸	CKS1B	P61024	2/20	0.47

▸	SKP1	P63208	2/20	0.47

▸	SKP2	Q13309	2/20	0.47

▸	DDB1	Q16531	1/20	0.43

▸	CRBN	Q96SW2	1/20	0.43

▸	MAP4K4	O95819	1/20	0.41

▸	FLT3	P36888	1/20	0.40

▸	TYRO3	Q06418	1/20	0.40

▸	MERTK	Q12866	1/20	0.40

▸	GAS6	Q14393	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3486592	0.86	GPR119 (0.67)	GPR119CKS1BSKP1SKP2
SCHEMBL20468831	0.77	CYP11B2 (0.55)	GPR119
SCHEMBL23560770	0.77	CKS1B (0.57)	GPR119CKS1BSKP1SKP2DDB1
SCHEMBL29029935	0.76	GPR119 (0.56)	GPR119CKS1BSKP1SKP2DDB1
SCHEMBL19602840	0.76	CKS1B (0.54)	GPR119CKS1BSKP1SKP2MAP4K4
SCHEMBL30395474	0.76	GPR119 (0.56)	GPR119CKS1BSKP1SKP2DDB1
SCHEMBL1432688	0.76	CKS1B (0.56)	GPR119CKS1BSKP1SKP2MAP4K4
SCHEMBL1432444	0.76	CKS1B (0.56)	GPR119CKS1BSKP1SKP2MAP4K4
SCHEMBL30546217	0.75	GPR119 (0.54)	GPR119CKS1BSKP1SKP2MAP4K4
SCHEMBL24369743	0.75	CKS1B (0.56)	GPR119CKS1BSKP1SKP2MAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2017069226-A1	NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND	田辺三菱製薬株式会社	2017-04-27	—	—	WO	disclosed