Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1873324 | 0.89 | POLB (0.54) | CA2POLBESR2ADRA1DADRA1A | |
| SCHEMBL1875160 | 0.87 | POLB (0.46) | CA2POLBESR2ADRA1DADRA1A | |
| SCHEMBL1876054 | 0.86 | CA2 (0.44) | CA2POLBESR2ADRA1DADRA1A | |
| SCHEMBL1081154 | 0.85 | CA2 (0.40) | CA2POLBESR2ADRA1DADRA1A | |
| SCHEMBL1042558 | 0.84 | CA2 (0.41) | CA2POLBESR2ADRA1DADRA1A | |
| SCHEMBL1083037 | 0.83 | ADRA1D (0.46) | ADRA1DADRA1AADRA1BHTR1AALDH1A1 | |
| SCHEMBL1878734 | 0.83 | SMN1; SMN2 (0.41) | CA2POLBESR2ADRA1DADRA1A | |
| SCHEMBL1880014 | 0.83 | CA2 (0.40) | CA2POLBESR2ADRA1DADRA1A | |
| SCHEMBL1080215 | 0.82 | CA2 (0.46) | CA2POLBESR2ALDH1A1HPGD | |
| SCHEMBL1889166 | 0.82 | CA2 (0.46) | CA2POLBESR2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105462-A1 | MODULATORS OF DOPAMINE NEUROTRANSMISSION | NSAB, FILIAL AF NEUROSEARCH SWEDEN AB, SVERIGE (DK) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105462-A1 | MODULATORS OF DOPAMINE NEUROTRANSMISSION | DBH, SLC18A2, SLC6A3 | CA2 3728/4885POLB 4159/4885ESR2 3143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.