Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | ACHE | P22303 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3778133 | 0.82 | ALDH1A1 (0.59) | ALDH1A1POLBLMNAACHEPKM | |
| SCHEMBL3646718 | 0.82 | ALDH1A1 (0.59) | ALDH1A1POLBLMNAACHEPKM | |
| SCHEMBL3227122 | 0.82 | KMT2A (0.70) | ALDH1A1POLBLMNAACHEPKM | |
| SCHEMBL3778136 | 0.82 | ALDH1A1 (0.59) | ALDH1A1POLBLMNAACHEPKM | |
| SCHEMBL3227131 | 0.82 | KMT2A (0.70) | ALDH1A1POLBLMNAACHEPKM | |
| SCHEMBL14990609 | 0.81 | ACHE (0.55) | ALDH1A1POLBLMNAACHEPKM | |
| SCHEMBL14990608 | 0.81 | ACHE (0.55) | ALDH1A1POLBLMNAACHEPKM | |
| SCHEMBL5036713 | 0.81 | ALDH1A1 (0.58) | ALDH1A1POLBLMNAACHEPKM | |
| SCHEMBL21124304 | 0.81 | ACHE (0.57) | ALDH1A1POLBLMNAACHEPKM | |
| SCHEMBL1791317 | 0.80 | KMT2A (0.58) | ALDH1A1POLBLMNAACHEPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017070794-A1 | PROCESS FOR THE PREPARATION OF 2-[2-(2-AMINO-2-CARBOXY-ETHYLAMINO)-2-CARBOXY-ETHYLAMINO]-SUCCINIC ACID (AM-A) AND ANALOGS AND DERIVATIVES THEREOF | MCMASTER UNIVERSITY (CA) | 2017-05-04 | — | — | WO | disclosed |