Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3778133 | 1.00 | ALDH1A1 (0.59) | ALDH1A1POLBLMNAACHEPKM | |
| SCHEMBL3646718 | 1.00 | ALDH1A1 (0.59) | ALDH1A1POLBLMNAACHEPKM | |
| SCHEMBL18794812 | 0.82 | ALDH1A1 (0.69) | ALDH1A1POLBLMNAACHEPKM | |
| SCHEMBL3227122 | 0.77 | KMT2A (0.70) | ALDH1A1POLBLMNAACHEPKM | |
| SCHEMBL3227131 | 0.77 | KMT2A (0.70) | ALDH1A1POLBLMNAACHEPKM | |
| SCHEMBL22308528 | 0.77 | ACHE (0.51) | ALDH1A1LMNAACHESMN1; SMN2 | |
| SCHEMBL1791317 | 0.75 | KMT2A (0.58) | ALDH1A1POLBLMNAACHEPKM | |
| SCHEMBL13958398 | 0.75 | TSHR (0.38) | ALDH1A1POLBLMNAACHEKMT2A | |
| SCHEMBL291869 | 0.75 | ALDH1A1 (0.53) | ALDH1A1POLBLMNAACHEPKM | |
| SCHEMBL291871 | 0.75 | ALDH1A1 (0.53) | ALDH1A1POLBLMNAACHEPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317863-A1 | Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions and Uses Thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317863-A1 | Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions and Uses Thereof | NR3C1, MC2R, NR3C2 | ALDH1A1 4038/4885POLB 3592/4885LMNA 3191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.