Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6096659 | 1.00 | ALDH1A1 (0.56) | ALDH1A1POLBLMNANPC1KMT2A | |
| SCHEMBL6096663 | 1.00 | ALDH1A1 (0.56) | ALDH1A1POLBLMNANPC1KMT2A | |
| SCHEMBL19243674 | 0.87 | ALDH1A1 (0.52) | ALDH1A1POLBLMNANPC1KMT2A | |
| SCHEMBL19243532 | 0.87 | ALDH1A1 (0.52) | ALDH1A1POLBLMNANPC1KMT2A | |
| SCHEMBL16310107 | 0.87 | NPC1 (0.51) | ALDH1A1POLBLMNANPC1KMT2A | |
| SCHEMBL5702208 | 0.86 | NPC1 (0.58) | ALDH1A1POLBLMNANPC1KMT2A | |
| SCHEMBL5701909 | 0.86 | NPC1 (0.58) | ALDH1A1POLBLMNANPC1KMT2A | |
| SCHEMBL6928231 | 0.86 | NPC1 (0.58) | ALDH1A1POLBLMNANPC1KMT2A | |
| SCHEMBL6926208 | 0.85 | ALDH1A1 (0.59) | ALDH1A1LMNANPC1KMT2AMEN1 | |
| SCHEMBL5065638 | 0.85 | ALDH1A1 (0.59) | ALDH1A1LMNANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017070794-A1 | PROCESS FOR THE PREPARATION OF 2-[2-(2-AMINO-2-CARBOXY-ETHYLAMINO)-2-CARBOXY-ETHYLAMINO]-SUCCINIC ACID (AM-A) AND ANALOGS AND DERIVATIVES THEREOF | MCMASTER UNIVERSITY (CA) | 2017-05-04 | — | — | WO | disclosed |