Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702208 | 1.00 | NPC1 (0.58) | NPC1ALDH1A1KMT2AMCOLN3MEN1 | |
| SCHEMBL6928231 | 1.00 | NPC1 (0.58) | NPC1ALDH1A1KMT2AMCOLN3MEN1 | |
| SCHEMBL8882067 | 0.93 | ALDH1A1 (0.59) | NPC1ALDH1A1KMT2AMCOLN3MEN1 | |
| SCHEMBL5065638 | 0.93 | ALDH1A1 (0.59) | NPC1ALDH1A1KMT2AMCOLN3MEN1 | |
| SCHEMBL6926208 | 0.93 | ALDH1A1 (0.59) | NPC1ALDH1A1KMT2AMCOLN3MEN1 | |
| SCHEMBL18337954 | 0.92 | ALDH1A1 (0.65) | NPC1ALDH1A1KMT2AMCOLN3MEN1 | |
| SCHEMBL18337953 | 0.92 | ALDH1A1 (0.65) | NPC1ALDH1A1KMT2AMCOLN3MEN1 | |
| SCHEMBL18794875 | 0.86 | ALDH1A1 (0.56) | NPC1ALDH1A1KMT2AMCOLN3MEN1 | |
| SCHEMBL6096659 | 0.86 | ALDH1A1 (0.56) | NPC1ALDH1A1KMT2AMCOLN3MEN1 | |
| SCHEMBL6096663 | 0.86 | ALDH1A1 (0.56) | NPC1ALDH1A1KMT2AMCOLN3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974670-B1 | Process for producing optically active N-substituted azetidine-2-carboxylic acid compound | SUMITOMO CHEMICAL CO (JP) | 2006-09-13 | — | — | EP | disclosed |
| US-6143554-A | Process for producing optically active n-substituted azetidine-2 carboxylic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0974670-A2 | Process for producing optically active N-substituted azetidine-2-carboxylic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-01-26 | — | — | EP | disclosed |