Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6096659 | 1.00 | ALDH1A1 (0.56) | ALDH1A1POLBLMNANPC1KMT2A | |
| SCHEMBL18794875 | 1.00 | ALDH1A1 (0.56) | ALDH1A1POLBLMNANPC1KMT2A | |
| SCHEMBL19243674 | 0.87 | ALDH1A1 (0.52) | ALDH1A1POLBLMNANPC1KMT2A | |
| SCHEMBL19243532 | 0.87 | ALDH1A1 (0.52) | ALDH1A1POLBLMNANPC1KMT2A | |
| SCHEMBL16310107 | 0.87 | NPC1 (0.51) | ALDH1A1POLBLMNANPC1KMT2A | |
| SCHEMBL5702208 | 0.86 | NPC1 (0.58) | ALDH1A1POLBLMNANPC1KMT2A | |
| SCHEMBL5701909 | 0.86 | NPC1 (0.58) | ALDH1A1POLBLMNANPC1KMT2A | |
| SCHEMBL6928231 | 0.86 | NPC1 (0.58) | ALDH1A1POLBLMNANPC1KMT2A | |
| SCHEMBL6926208 | 0.85 | ALDH1A1 (0.59) | ALDH1A1LMNANPC1KMT2AMEN1 | |
| SCHEMBL5065638 | 0.85 | ALDH1A1 (0.59) | ALDH1A1LMNANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118256591-A | Cyclic peptide compound having high membrane permeability and library comprising same | 中外制药株式会社 | 2024-06-28 | — | — | CN | disclosed |
| CN-110869544-B | Cyclic peptide compound having high membrane permeability and library comprising same | 中外制药株式会社 | 2024-03-08 | — | — | CN | disclosed |
| US-20200131669-A1 | CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-04-30 | — | — | US | disclosed |
| EP-3636807-A1 | CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 2020-04-15 | — | — | EP | disclosed |
| CN-110869544-A | Cyclic peptide compound having high membrane permeability and library containing same | 中外制药株式会社 | 2020-03-06 | — | — | CN | disclosed |
| WO-2017070794-A1 | PROCESS FOR THE PREPARATION OF 2-[2-(2-AMINO-2-CARBOXY-ETHYLAMINO)-2-CARBOXY-ETHYLAMINO]-SUCCINIC ACID (AM-A) AND ANALOGS AND DERIVATIVES THEREOF | MCMASTER UNIVERSITY (CA) | 2017-05-04 | — | — | WO | disclosed |
| US-7109352-B2 | Process for producing optically active amino acid derivatives | KANEKA CORPORATION (JP) | 2006-09-19 | — | — | US | disclosed |
| US-20050143586-A1 | Process for producing optically active amino acid derivatives | KANEKA CORPORATION (JP) | 2005-06-30 | — | — | US | disclosed |
| US-6720449-B2 | N-PROTECTING AN OPTICALLY ACTIVE 3-HALOALANINE DERIVATIVE FOLLOWED BY CYCLIZATION FOR AZIRIDINE-2-CARBOXYLIC ACID DERIVATIVES | KANEKA CORPORATION (JP) | 2004-04-13 | — | — | US | disclosed |
| EP-1321454-A1 | PROCESS FOR THE REMOVAL OF NITROBENZENESULFONYL | Kaneka Corporation (JP) | 2003-06-25 | — | — | EP | disclosed |
| US-20030032814-A1 | Process for preparing optically active amino acid derivatives | KANEKA CORPORATION (JP) | 2003-02-13 | — | — | US | disclosed |
| US-6515179-B2 | Reacting nitrobenzenesulfonyl group containing compound contacting with alkali metal alkoxide | KANEKA CORPORATION (JP) | 2003-02-04 | — | — | US | disclosed |
| US-20030009056-A1 | PROCESS FOR THE REMOVAL OF NITROBENZENESULFONYL | KANEKA CORPORATION (JP) | 2003-01-09 | — | — | US | disclosed |
| EP-1179530-A1 | PROCESSES FOR PREPARING OPTICALLY ACTIVE AMINO ACID DERIVATIVES | Kaneka Corporation (JP) | 2002-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143586-A1 | Process for producing optically active amino acid derivatives | NPEPPS, AAAS, DDC | ALDH1A1 1582/4885POLB 3616/4885LMNA 2582/4885 |
| US-20200131669-A1 | CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME | VIP, SLC7A1, TRPV1 | ALDH1A1 4817/4885POLB 4724/4885LMNA 4187/4885 |
| US-20030032814-A1 | Process for preparing optically active amino acid derivatives | NPEPPS, AAAS, DDC | ALDH1A1 1618/4885POLB 3399/4885LMNA 1982/4885 |
| US-20030009056-A1 | PROCESS FOR THE REMOVAL OF NITROBENZENESULFONYL | NAAA, TST, AADAC | ALDH1A1 2030/4885POLB 1570/4885LMNA 4195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.