Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18819816 | 0.87 | TDP1 (0.52) | TDP1ALDH1A1RXFP1NR4A2ERN1 | |
| SCHEMBL6965074 | 0.81 | ALDH1A1 (0.46) | TDP1ALDH1A1RXFP1HTR3AGAA | |
| SCHEMBL4194871 | 0.76 | KMT2A (0.45) | TDP1ALDH1A1RXFP1POLBHSD17B10 | |
| SCHEMBL4488260 | 0.76 | ALDH1A1 (0.70) | TDP1ALDH1A1RXFP1NR4A2POLB | |
| SCHEMBL31345649 | 0.76 | ALDH1A1 (0.70) | TDP1ALDH1A1RXFP1NR4A2POLB | |
| SCHEMBL3748357 | 0.74 | CCR1 (0.48) | TDP1ALDH1A1NR4A2POLBHTR3E | |
| SCHEMBL7608692 | 0.74 | NR4A2 (0.52) | ALDH1A1RXFP1NR4A2POLBPDGFRB | |
| SCHEMBL28208080 | 0.74 | NR4A2 (0.44) | ALDH1A1RXFP1NR4A2POLBPDGFRB | |
| SCHEMBL18795087 | 0.72 | KMT2A (0.49) | ALDH1A1RXFP1NR4A2POLBPDGFRB | |
| SCHEMBL28277834 | 0.72 | POLB (0.45) | TDP1ALDH1A1NR4A2POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108430986-B | Fused bicyclic heterocyclic derivatives as pest control agents | 拜耳作物科学股份公司 | 2021-08-31 | — | — | CN | disclosed |
| US-10550116-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-04 | — | — | US | disclosed |
| US-10550116-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-04 | — | — | US | disclosed |
| US-20180305353-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-10-25 | — | — | US | disclosed |
| EP-3368521-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-09-05 | — | — | EP | disclosed |
| CN-108430986-A | fused bicyclic heterocyclic derivatives as pest control agents | 拜耳作物科学股份公司 | 2018-08-21 | — | — | CN | disclosed |
| WO-2017072039-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-04 | — | — | WO | disclosed |
| WO-2017072039-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180305353-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, BCHE, ACHE | TDP1 2328/4885ALDH1A1 468/4885RXFP1 1735/4885 |
| US-10550116-B2 | Fused bicyclic heterocycle derivatives as pesticides | DDT, BCHE, ACHE | TDP1 2328/4885ALDH1A1 468/4885RXFP1 1735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.