Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 3/20 | 0.52 |
| ▸ | ATP4B | P51164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 9/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 9/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 9/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 9/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 9/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 9/20 | 0.47 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062520 | 0.85 | ATP4A (0.58) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL1875165 | 0.81 | LMNA (0.55) | ATP4AATP4BHDAC6PSEN1PSEN2 | |
| SCHEMBL7853457 | 0.77 | ATP4A (0.61) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL12952654 | 0.77 | ALDH1A1 (0.42) | MEN1KMT2ARNASEH1LMNAHPGD | |
| SCHEMBL12638590 | 0.77 | KDM4E (0.42) | RNASEH1LMNAHPGDERCC1FEN1 | |
| SCHEMBL17802255 | 0.75 | ATP4A (0.53) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL903268 | 0.72 | ATP4A (0.65) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL823323 | 0.72 | ALDH1A1 (0.66) | MEN1MAPK1KMT2ALMNAHPGD | |
| SCHEMBL10379243 | 0.72 | PSEN1 (0.51) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL11064908 | 0.72 | ATP4A (0.68) | ATP4AATP4BMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937678-B1 | HIV INTEGRASE INHIBITORS | ANGELETTI P IST RICHERCHE BIO (IT) | 2011-07-27 | — | — | EP | disclosed |
| US-7939537-B2 | HIV integrase inhibitors | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2011-05-10 | — | — | US | disclosed |
| US-20090221571-A1 | HIV INTEGRASE INHIBITORS | MSD ITALIA S.R.L. (IT) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221571-A1 | HIV INTEGRASE INHIBITORS | TYMP, CDK2, TYMS | ATP4A 1521/4885ATP4B 1371/4885MEN1 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.