Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669066 | 0.80 | — | — | |
| SCHEMBL10913604 | 0.78 | ALDH1A1 (0.39) | NR1H2NR1H3ALDH1A1TSHR | |
| SCHEMBL10941267 | 0.78 | NR1H2 (0.38) | NR1H2NR1H3ALDH1A1TSHR | |
| SCHEMBL3700317 | 0.77 | NR1H2 (0.37) | NR1H2NR1H3ALDH1A1TSHR | |
| SCHEMBL2003493 | 0.74 | APOBEC3G (0.38) | NR1H2NR1H3ALDH1A1 | |
| SCHEMBL18796346 | 0.74 | — | — | |
| SCHEMBL1147728 | 0.71 | NR1H2 (0.53) | NR1H2NR1H3ALDH1A1TSHRMEN1 | |
| SCHEMBL2141988 | 0.69 | IDO1 (0.34) | HDAC8 | |
| SCHEMBL18796087 | 0.69 | MAPT (0.32) | HDAC8 | |
| SCHEMBL29719052 | 0.69 | IDO1 (0.34) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349897-B | Trisubstituted silylphenoxyheterocycles and analogs | 拜耳作物科学股份公司 | 2022-03-04 | — | — | CN | disclosed |
| EP-3368514-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | Bayer CropScience Aktiengesellschaft (DE) | 2018-09-05 | — | — | EP | disclosed |
| WO-2017072283-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-04 | — | — | WO | disclosed |