Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | PDXK | O00764 | 2/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2007121 | 0.78 | APOBEC3G (0.41) | APOBEC3GNR1H2NR1H3PDXKPDCD1 | |
| SCHEMBL10941267 | 0.76 | NR1H2 (0.38) | NR1H2NR1H3ALDH1A1 | |
| SCHEMBL10913604 | 0.76 | ALDH1A1 (0.39) | NR1H2NR1H3ALDH1A1 | |
| SCHEMBL9206225 | 0.74 | APOBEC3G (0.48) | APOBEC3GPDCD1CD274MAOB | |
| SCHEMBL18796002 | 0.74 | NR1H2 (0.37) | NR1H2NR1H3ALDH1A1 | |
| SCHEMBL3700317 | 0.74 | NR1H2 (0.37) | NR1H2NR1H3ALDH1A1 | |
| SCHEMBL12572225 | 0.70 | APOBEC3G (0.41) | APOBEC3GPDCD1CD274MAOB | |
| SCHEMBL556905 | 0.70 | LIPG (0.39) | APOBEC3GNR1H2NR1H3 | |
| Propene SCHEMBL6298688 | 0.69 | APOBEC3G (0.46) | APOBEC3GPDXKPDCD1CD274GABRA1 | |
| SCHEMBL2006118 | 0.69 | APOBEC3G (0.39) | APOBEC3GPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960571-B2 | Silicon-based cross-coupling reagent and production method of organic compound using the same | KYOTO UNIVERSITY (JP) | 2011-06-14 | — | — | US | disclosed |
| US-20090069577-A1 | Silicon-Based Cross-Coupling Reagent and Production Method of Organic Compound Using the Same | KYOTO UNIVERSITY (JP) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069577-A1 | Silicon-Based Cross-Coupling Reagent and Production Method of Organic Compound Using the Same | DNMT1, TET3, CTCF | APOBEC3G 3259/4885NR1H2 3400/4885NR1H3 2771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.