Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | WRN | Q14191 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16533055 | 0.94 | GSK3A (0.41) | GSK3AGSK3BHTTLMNASMN1; SMN2 | |
| SCHEMBL15362286 | 0.94 | GSK3A (0.41) | GSK3AGSK3BHTTLMNASMN1; SMN2 | |
| SCHEMBL17831028 | 0.72 | HTT (0.34) | HTTLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL10032059 | 0.71 | SPR (0.42) | GSK3AGSK3BHTTLMNASMN1; SMN2 | |
| SCHEMBL515802 | 0.70 | GSK3A (0.36) | GSK3AGSK3BHTTALDH1A1HPGD | |
| SCHEMBL10067032 | 0.70 | GSK3A (0.36) | GSK3AGSK3BHTTALDH1A1HPGD | |
| SCHEMBL15235369 | 0.69 | MTNR1A (0.53) | GSK3AGSK3BHTTLMNASMN1; SMN2 | |
| SCHEMBL16772157 | 0.69 | MGLL (0.36) | HTTLMNASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL12590044 | 0.69 | AKT1 (0.39) | GSK3AGSK3BHTTLMNASMN1; SMN2 | |
| SCHEMBL26707222 | 0.69 | AKT1 (0.41) | GSK3AGSK3BHTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368557-A1 | NEW POLYPEPTIDE | Affibody AB (SE) | 2018-09-05 | — | — | EP | disclosed |
| WO-2017072273-A1 | NEW POLYPEPTIDE | AFFIBODY AB (SE) | 2017-05-04 | — | — | WO | disclosed |