Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19273911 | 1.00 | GAA (0.46) | GAAMAPTALDH1A1HSD17B10CFTR | |
| SCHEMBL15628062 | 0.88 | ALDH1A1 (0.45) | GAAMAPTALDH1A1HSD17B10CFTR | |
| SCHEMBL5388881 | 0.86 | MAPT (0.43) | GAAMAPTALDH1A1HSD17B10CFTR | |
| SCHEMBL288333 | 0.86 | MAPT (0.43) | GAAMAPTALDH1A1HSD17B10CFTR | |
| SCHEMBL3156486 | 0.85 | ALDH1A1 (0.46) | GAAMAPTALDH1A1HSD17B10CFTR | |
| SCHEMBL14645210 | 0.85 | ALDH1A1 (0.46) | GAAMAPTALDH1A1HSD17B10CFTR | |
| SCHEMBL25662409 | 0.85 | MAPT (0.44) | GAAMAPTALDH1A1HSD17B10CFTR | |
| SCHEMBL31520049 | 0.85 | ALDH1A1 (0.46) | GAAMAPTALDH1A1HSD17B10CFTR | |
| SCHEMBL4351788 | 0.85 | ALDH1A1 (0.50) | GAAMAPTALDH1A1HSD17B10CFTR | |
| SCHEMBL4996617 | 0.84 | MAPT (0.42) | GAAMAPTALDH1A1HSD17B10CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667674-B2 | Antibacterial cyclic lipopeptides | VERSITECH LIMITED (CN) | 2023-06-06 | — | — | US | disclosed |
| US-11320438-B2 | Isotopic methods for measurement of tryptophan and metabolites thereof | ELECTROPHORETICS LIMITED (GB) | 2022-05-03 | — | — | US | disclosed |
| CN-108351360-B | Isotopic method for measuring tryptophan and metabolites thereof | 电泳有限公司 | 2022-03-04 | — | — | CN | disclosed |
| EP-3495354-A1 | IDO1 INHIBITOR AND PREPARATION METHOD AND APPLICATION THEREOF | Shandong Luye Pharmaceutical Co., Ltd. (CN) | 2019-06-12 | — | — | EP | disclosed |
| US-20190169140-A1 | IDO1 INHIBITOR AND PREPARATION METHOD AND APPLICATION THEREOF | SHANDONG LUYE PHARMACEUTICAL CO., LTD. (CN) | 2019-06-06 | — | — | US | disclosed |
| EP-3368905-A1 | ISOTOPIC METHODS FOR MEASUREMENT OF TRYPTOPHAN AND METABOLITES THEREOF | Electrophoretics Limited (GB) | 2018-09-05 | — | — | EP | disclosed |
| US-20180246118-A1 | ISOTOPIC METHODS FOR MEASUREMENT OF TRYPTOPHAN AND METABOLITES THEREOF | ELECTROPHORETICS LIMITED (GB) | 2018-08-30 | — | — | US | disclosed |
| WO-2017173932-A1 | ANTIBACTERIAL CYCLIC LIPOPEPTIDES | VERSITECH LIMITED (CN) | 2017-10-12 | — | — | WO | disclosed |
| WO-2017072368-A1 | ISOTOPIC METHODS FOR MEASUREMENT OF TRYPTOPHAN AND METABOLITES THEREOF | ELECTROPHORETICS LIMITED (GB) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667674-B2 | Antibacterial cyclic lipopeptides | PTMS, NRDC, LNPEP | GAA 1031/4885MAPT 4782/4885ALDH1A1 4793/4885 |
| US-20190169140-A1 | IDO1 INHIBITOR AND PREPARATION METHOD AND APPLICATION THEREOF | IDO1, IDO2, INMT | GAA 381/4885MAPT 2353/4885ALDH1A1 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.