Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 6/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | SLC26A3 | P40879 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18820260 | 0.86 | PDE3B (0.61) | PDE3BPDE3AIL4I1KDM4EGAA | |
| SCHEMBL18796736 | 0.85 | PDE3B (0.77) | PDE3BPDE3AKDM4EGAAMEN1 | |
| SCHEMBL18796682 | 0.80 | PDE10A (0.51) | PDE3BPDE3AIL4I1 | |
| SCHEMBL18796699 | 0.79 | PDE3B (0.54) | PDE3BPDE3AKDM4EHPGDHSD17B10 | |
| SCHEMBL18796704 | 0.78 | PDE3B (0.53) | PDE3BPDE3AKDM4EHPGDHSD17B10 | |
| SCHEMBL18796709 | 0.77 | PDE3B (0.66) | PDE3BPDE3AIL4I1KDM4EHPGD | |
| SCHEMBL18796747 | 0.76 | PDE3B (0.82) | PDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL28045795 | 0.75 | HCAR2 (0.48) | HCAR2MEN1KMT2A | |
| SCHEMBL11818397 | 0.75 | HCAR2 (0.50) | HCAR2KDM4EMEN1KMT2APTGER1 | |
| SCHEMBL11820882 | 0.75 | HCAR2 (0.50) | HCAR2KDM4EHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017072796-A1 | 2-PYRIDONE BASED COMPOUNDS USEFUL AS POTENTIAL PHOSPHODIESTERASE3A (PDE3A)INHIBITORS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-05-04 | — | — | WO | disclosed |