Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27902935 | 0.84 | HNF4A (0.50) | HNF4A | |
| SCHEMBL18796660 | 0.75 | PDE3B (0.55) | HCAR2MEN1KMT2A | |
| SCHEMBL28220773 | 0.75 | TSHR (0.57) | HCAR2MEN1KMT2AEGFRERBB2 | |
| SCHEMBL11820882 | 0.75 | HCAR2 (0.50) | HCAR2MEN1KMT2AEGFRERBB2 | |
| SCHEMBL11818397 | 0.75 | HCAR2 (0.50) | HCAR2MEN1KMT2AMAOBMAOA | |
| SCHEMBL27633121 | 0.74 | ALDH1A1 (0.48) | MEN1KMT2AHNF4A | |
| SCHEMBL28028683 | 0.73 | TTR (0.46) | MEN1KMT2ASORT1MYC | |
| SCHEMBL27463279 | 0.73 | KDM4E (0.47) | MEN1KMT2AHNF4A | |
| SCHEMBL27542160 | 0.72 | TSHR (0.53) | HCAR2MEN1KMT2AMAOBMRGPRX4 | |
| SCHEMBL28050503 | 0.71 | MRGPRX4 (0.54) | HCAR2MEN1KMT2AEGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105283182-A | Treatment of cancer with heterocyclic inhibitors of glutaminase | CALITHERA BIOSCIENCES INC | 2016-01-27 | — | — | CN | disclosed |