Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.47 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1874510 | 0.98 | TACR1 (0.57) | TACR1TSHRCA1CA2CA7 | |
| SCHEMBL5102451 | 0.89 | TACR1 (0.47) | TACR1GABBR2GABBR1 | |
| SCHEMBL21239604 | 0.88 | TACR1 (0.61) | TACR1TSHRCA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL1883137 | 0.87 | TACR1 (0.46) | TACR1GABBR2GABBR1 | |
| SCHEMBL5095821 | 0.84 | TACR1 (0.52) | TACR1 | |
| SCHEMBL5099163 | 0.84 | TACR1 (0.70) | TACR1 | |
| Hydrochloric Acid SCHEMBL1871311 | 0.82 | TACR1 (0.68) | TACR1 | |
| Hydrochloric Acid SCHEMBL1874446 | 0.82 | TACR1 (0.51) | TACR1 | |
| SCHEMBL2628027 | 0.82 | TACR1 (0.47) | TACR1TSHRGABBR2GABBR1HTR2A | |
| SCHEMBL5109698 | 0.81 | TACR1 (0.54) | TACR1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1870396-B1 | BENZYLOXYPROPYLAMINE DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2012-10-31 | — | — | EP | disclosed |
| US-7939552-B2 | Tachykinin receptor anatgonist; good transfer into blood; long half-life; stability; bradycardial agents; antiinflammatory agents ; antallergens; analgesics; antiemetics; irritable bowel disorders; skin disorders; antidepressants; antiischemic agents ; anxiolytic agents; autoimmune diseases; muscle relax | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2011-05-10 | — | — | US | disclosed |
| US-20080262230-A1 | Benzyloxypropylamine Derivative | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2008-10-23 | — | — | US | disclosed |
| EP-1870396-A1 | BENZYLOXYPROPYLAMINE DERIVATIVE | Nippon Zoki Pharmaceutical Co. Ltd. (JP) | 2007-12-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262230-A1 | Benzyloxypropylamine Derivative | BDKRB2, BDKRB1, PNMT | TACR1 10/4885TSHR 1236/4885CA1 4198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.