Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 11/20 | 0.54 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1871875 | 0.99 | TACR1 (0.53) | TACR1IDO1NPC1ALDH1A1CYP2D6 | |
| SCHEMBL1879700 | 0.81 | TACR1 (0.59) | TACR1TAAR1 | |
| Hydrochloric Acid SCHEMBL1874510 | 0.80 | TACR1 (0.57) | TACR1 | |
| SCHEMBL5102451 | 0.78 | TACR1 (0.47) | TACR1IDO1CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL1883137 | 0.77 | TACR1 (0.46) | TACR1IDO1CHRNB2CHRNA4 | |
| SCHEMBL5099163 | 0.77 | TACR1 (0.70) | TACR1 | |
| SCHEMBL5095821 | 0.77 | TACR1 (0.52) | TACR1IDO1TDO2 | |
| Hydrochloric Acid SCHEMBL1874446 | 0.75 | TACR1 (0.51) | TACR1IDO1TDO2 | |
| Hydrochloric Acid SCHEMBL1871311 | 0.75 | TACR1 (0.68) | TACR1 | |
| SCHEMBL5109834 | 0.75 | TACR1 (0.42) | TACR1NPC1PLA2G1BPOLBATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1870396-B1 | BENZYLOXYPROPYLAMINE DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2012-10-31 | — | — | EP | disclosed |
| US-20080262230-A1 | Benzyloxypropylamine Derivative | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2008-10-23 | — | — | US | disclosed |
| EP-1870396-A1 | BENZYLOXYPROPYLAMINE DERIVATIVE | Nippon Zoki Pharmaceutical Co. Ltd. (JP) | 2007-12-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262230-A1 | Benzyloxypropylamine Derivative | BDKRB2, BDKRB1, PNMT | TACR1 10/4885IDO1 1680/4885NPC1 1353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.