Pivalate

Pivalate

SCHEMBL18797178

CC(C)(C)C(=O)O.COc1ccc(CN)cc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.54
LDHA P00338 1/20 0.51
LOXL2 Q9Y4K0 1/20 0.49
TAAR1 Q96RJ0 1/20 0.48
HTT P42858 1/20 0.47
KLKB1 P03952 1/20 0.47
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
POLB P06746 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CTBP2 P56545 1/20 0.46
F2RL1 P55085 1/20 0.46
SLC6A4 P31645 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
EPHX1 P07099 1/20 0.46
MAPK1 P28482 1/20 0.45
HSD17B10 Q99714 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL25353301 0.89 MAOB (0.61) MAOBLDHALOXL2TAAR1HTT
Trifluoroacetic Acid SCHEMBL6220574 0.88 LDHA (0.54) MAOBLDHALOXL2TAAR1SLC6A4
Trifluoroacetic Acid SCHEMBL6317983 0.88 LDHA (0.54) MAOBLDHALOXL2TAAR1SLC6A4
Acetic Acid SCHEMBL28065462 0.87 MAOB (0.59) MAOBLDHALOXL2TAAR1HTT
Methyl Alcohol SCHEMBL28283803 0.82 MAOB (0.68) MAOBLOXL2TAAR1SLC6A4CA1
SCHEMBL4951818 0.82 MAOB (0.73) MAOBTAAR1SMN1; SMN2SLC6A4CA1
SCHEMBL8755 0.82 MAOB (0.73) MAOBTAAR1SMN1; SMN2SLC6A4CA1
Aminomethylbenzoic Acid SCHEMBL5215159 0.82 CA1 (0.71) MAOBLOXL2RAB9ANPC1POLB
Hypochlorous Acid SCHEMBL10950049 0.81 MAOB (0.66) MAOBLOXL2TAAR1SLC6A4CA1
Hydrochloric Acid SCHEMBL1715149 0.80 MAOB (0.77) MAOBTAAR1SLC6A4CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3728381-A1 FROST-RESISTANT ADHESIVES BASED ON POLYISOCYANATES Covestro Deutschland AG (DE) 2020-10-28 EP disclosed
EP-3368632-A1 POLYISOCYANURATE BASED CEMENT FOR WELLBORE FLUID LOSS PREVENTION Covestro LLC (US) 2018-09-05 EP disclosed
WO-2017074928-A1 POLYISOCYANURATE BASED CEMENT FOR WELLBORE FLUID LOSS PREVENTION COVESTRO LLC (US) 2017-05-04 WO disclosed