Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.71 |
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.58 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.53 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL25353301 | 0.89 | MAOB (0.61) | CA1CA2RAB9ASMN1; SMN2NPC1 | |
| Acetic Acid SCHEMBL28065462 | 0.87 | MAOB (0.59) | CA1CA2RAB9ASMN1; SMN2NPC1 | |
| Aminomethylbenzoic Acid SCHEMBL5213365 | 0.85 | MMP13 (0.62) | CA1CA2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL26116709 | 0.85 | SRD5A2 (0.66) | RAB9ASMN1; SMN2NPC1POLBLOXL2 | |
| SCHEMBL12243323 | 0.85 | CA1 (0.77) | CA1CA2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11464459 | 0.85 | CA1 (0.77) | CA1CA2RAB9ASMN1; SMN2NPC1 | |
| P-Anisic Acid SCHEMBL17509999 | 0.85 | CA1 (0.91) | CA1CA2RAB9ASMN1; SMN2NPC1 | |
| Aminomethylbenzoic Acid SCHEMBL11755138 | 0.85 | ALDH1A1 (0.61) | SMN1; SMN2POLBLOXL2TSHRTP53 | |
| P-Anisic Acid SCHEMBL1157044 | 0.84 | CA1 (1.00) | CA1CA2RAB9ASMN1; SMN2NPC1 | |
| Aminomethylbenzoic Acid SCHEMBL9344424 | 0.84 | ALDH1A1 (0.60) | CA1CA2SMN1; SMN2POLBLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-B1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2007-04-04 | — | — | EP | claimed |