Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21539650 | 0.89 | MTNR1A (0.35) | MTNR1AMTNR1B | |
| SCHEMBL18798014 | 0.89 | MTNR1A (0.34) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL23837421 | 0.86 | MTNR1A (0.33) | MTNR1AMTNR1B | |
| SCHEMBL18797975 | 0.86 | — | — | |
| SCHEMBL22667375 | 0.85 | MTNR1A (0.34) | MTNR1AMTNR1B | |
| SCHEMBL23130054 | 0.85 | MTNR1A (0.36) | MTNR1AMTNR1BALDH1A1HTT | |
| SCHEMBL17347753 | 0.85 | MTNR1A (0.36) | MTNR1AMTNR1BALDH1A1HTT | |
| SCHEMBL19228029 | 0.82 | MTNR1A (0.32) | MTNR1AMTNR1B | |
| SCHEMBL19228023 | 0.82 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL18797996 | 0.80 | CASP3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637504-B2 | Beta-lactamase inhibitors | VenatoRx Pharmaceuticals, Inc. (US) | 2017-05-02 | — | — | US | disclosed |