Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.44 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 8/20 | 0.41 |
| ▸ | CA9 | Q16790 | 8/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15760447 | 0.84 | LMNA (0.59) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| SCHEMBL5479694 | 0.84 | LMNA (0.67) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| SCHEMBL18800087 | 0.83 | LMNA (0.53) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| SCHEMBL18913377 | 0.83 | LMNA (0.54) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| SCHEMBL18798673 | 0.83 | LMNA (0.50) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| SCHEMBL14999666 | 0.82 | LMNA (0.64) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| SCHEMBL11399951 | 0.82 | LMNA (0.64) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| SCHEMBL18800068 | 0.81 | ALDH1A1 (0.48) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| SCHEMBL15760865 | 0.81 | LMNA (0.60) | LMNAKMT2AKDM4ECYP1A2GRIA1 | |
| SCHEMBL11396051 | 0.81 | LMNA (0.62) | LMNAKMT2AKDM4ECYP1A2GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9636404-B2 | Pharmaceutical composition comprising modified hemoglobin-based therapeutic agent for cancer targeting treatment and diagnostic imaging | VISION GLOBAL HOLDINGS LTD. (CN) | 2017-05-02 | — | — | US | disclosed |
| US-9636404-B2 | Pharmaceutical composition comprising modified hemoglobin-based therapeutic agent for cancer targeting treatment and diagnostic imaging | VISION GLOBAL HOLDINGS LTD. (CN) | 2017-05-02 | — | — | US | disclosed |