SCHEMBL1879893

SCHEMBL1879893

CC(C)(F)OC(=O)C(=C(F)F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5886622 0.86 ALDH1A1 (0.35) ALDH1A1MAPT
SCHEMBL6140603 0.81 ALDH1A1 (0.33) ALDH1A1MAPT
SCHEMBL2957666 0.76 MAPT (0.55) ALDH1A1MAPT
SCHEMBL5900905 0.75 ALDH1A1 (0.35) ALDH1A1MAPT
SCHEMBL3819533 0.74 ALDH1A1 (0.30) ALDH1A1MAPT
SCHEMBL2350046 0.73 ALDH1A1 (0.34) ALDH1A1MAPT
SCHEMBL10008404 0.72 THRB (0.31)
SCHEMBL9561617 0.71
SCHEMBL5886602 0.71 TSHR (0.37) ALDH1A1MAPT
SCHEMBL5886592 0.71 ALDH1A1 (0.39) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3847220-A1 UV-CURABLE HOT MELT ADHESIVE COMPOSITIONS FOR FLOORING APPLICATIONS BASF SE (DE) 2021-07-14 EP claimed
CN-108276658-A The preparation method of abrasion-proof self-lubricating composite material 武汉鼎瑞新材料有限责任公司 2018-07-13 CN claimed
CN-105061674-B A kind of formulation selection and new process of the silicone hydrogel contact lens of novel fluorine siloxanes 爱生华(苏州)光学有限公司 2018-04-13 CN claimed
US-20090104136-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME LIVING PROOF, INC. 2009-04-23 US claimed
EP-0424099-B1 Method of Preparing Polymeric Compositions for Oxygen Permeable Contact Lenses POLYMER TECHNOLOGY CORP (US) 1995-10-04 EP claimed
US-5032658-A Hardness, unsaturated ester POLYMER TECHNOLOGY CORPORATION (US) 1991-07-16 US claimed
EP-0424099-A2 Method of Preparing Polymeric Compositions for Oxygen Permeable Contact Lenses POLYMER TECHNOLOGY CORPORATION (US) 1991-04-24 EP claimed
EP-0351364-A2 Dimethylacrylamide-copolymer hydrogels with high oxygen permeability CIBA-GEIGY AG (CH) 1990-01-17 EP claimed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP disclosed
EP-3847220-A1 UV-CURABLE HOT MELT ADHESIVE COMPOSITIONS FOR FLOORING APPLICATIONS BASF SE (DE) 2021-07-14 EP disclosed
CN-112695525-A Flame-retardant waterproof and oil-proof finishing agent and preparation method thereof 京准化工技术(上海)有限公司 2021-04-23 CN disclosed
EP-3788083-A1 HIGH MOLAR MASS POLYMERS FROM A CONTINUOUS PROCESS BASF SE (DE) 2021-03-10 EP disclosed
CN-108329450-A High fluorine antifriction self-lubricating material 武汉鼎瑞新材料有限责任公司 2018-07-27 CN disclosed
CN-108276552-A The production method of fluorine material 武汉鼎瑞新材料有限责任公司 2018-07-13 CN disclosed
US-5034461-A Polyetherurethanesiloxane copolymer for contact lenses, also containing acrylate groups to provide high oxygen permeability BAUSCH & LOMB INCORPORATED (US) 1991-07-23 US disclosed
EP-0425436-A2 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA-GEIGY AG (CH) 1991-05-02 EP disclosed
EP-0401990-A2 Prepolymers useful in biomedical devices BAUSCH & LOMB INCORPORATED (US) 1990-12-12 EP disclosed
US-4861840-A Novel siloxanyl acrylic monomer and gas-permeable contact lenses made therefrom BARNES-HIND, INC. (US) 1989-08-29 US disclosed
EP-0293467-A1 NOVEL SILOXANYL ACRYLIC MONOMER AND GAS-PERMEABLE CONTACT LENSES MADE THEREFROM BARNES-HIND, INC. (US) 1988-12-07 EP disclosed
WO-1988004299-A1 NOVEL SILOXANYL ACRYLIC MONOMER AND GAS-PERMEABLE CONTACT LENSES MADE THEREFROM BARNES-HIND, INC. (US) 1988-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104136-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME TET1, TET2, TET3 ALDH1A1 457/4885MAPT 1213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.