SCHEMBL2957666

SCHEMBL2957666

COC(=O)C(=C(F)F)C(F)(F)F

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.55
ALDH1A1 P00352 3/20 0.55
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
XBP1 P17861 1/20 0.45
GPR35 Q9HC97 1/20 0.34
TET2 Q6N021 1/20 0.33
CES2 O00748 3/20 0.33
ACHE P22303 3/20 0.33
CES1 P23141 3/20 0.33
CA2 P00918 1/20 0.31
RAB9A P51151 3/20 0.30
NPC1 O15118 2/20 0.30
LMNA P02545 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
KDM4E B2RXH2 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3439542 0.80 ALDH1A1 (0.55) MAPTALDH1A1MEN1KMT2AXBP1
SCHEMBL5900905 0.79 ALDH1A1 (0.35) MAPTALDH1A1
SCHEMBL19807497 0.78 MAPT (0.48) MAPTALDH1A1MEN1KMT2AXBP1
SCHEMBL18655713 0.78 ALDH1A1 (0.53) MAPTALDH1A1MEN1KMT2AXBP1
SCHEMBL2350046 0.77 ALDH1A1 (0.34) MAPTALDH1A1
SCHEMBL20043784 0.76 MAPT (0.47) MAPTALDH1A1MEN1KMT2AXBP1
SCHEMBL5886622 0.76 ALDH1A1 (0.35) MAPTALDH1A1
SCHEMBL6140603 0.75 ALDH1A1 (0.33) MAPTALDH1A1
SCHEMBL5886602 0.75 TSHR (0.37) MAPTALDH1A1MEN1KMT2ACA2
SCHEMBL5886592 0.75 ALDH1A1 (0.39) MAPTALDH1A1MEN1KMT2AGPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894780-A High-strength strong-hydrophobic fluorine-containing proppant and preparation method thereof 西南石油大学 2023-04-04 CN claimed
US-20090104136-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME LIVING PROOF, INC. 2009-04-23 US claimed
CN-115894780-A High-strength strong-hydrophobic fluorine-containing proppant and preparation method thereof 西南石油大学 2023-04-04 CN disclosed
CN-115851254-A Double-hydrophobic modified quartz sand proppant and preparation method thereof 西南石油大学 2023-03-28 CN disclosed
CN-112480296-A Hydrophilic modified ethylene-chlorotrifluoroethylene copolymer, and preparation method and application thereof 浙江省化工研究院有限公司 2021-03-12 CN disclosed
US-20160038388-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME LIVING PROOF INC (US) 2016-02-11 US disclosed
US-20160038388-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME LIVING PROOF INC (US) 2016-02-11 US disclosed
US-9192553-B2 Hair care compositions and methods of treating hair using same LIVING PROOF, INC. (US) 2015-11-24 US disclosed
US-9192553-B2 Hair care compositions and methods of treating hair using same LIVING PROOF, INC. (US) 2015-11-24 US disclosed
US-9150491-B2 Bicyclohexane derivative compound and manufacturing method of the same MITSUBISHI GAS CHEMICAL COMPANY, INC (JP) 2015-10-06 US disclosed
US-8920889-B2 Optical film, polarizing plate, and image-forming display device FUJIFILM CORPORATION (JP) 2014-12-30 US disclosed
US-20090053175-A1 SUBSTITUTE PYRROLIDINE DERIVATIVES ENANTA PHARMACEUTICALS, INC. 2009-02-26 US disclosed
US-7078562-B2 Adamantane derivatives and resin compositions using the same as raw material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2006-07-18 US disclosed
US-7067692-B2 Production method of adamantyl acrylate compounds MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2006-06-27 US disclosed
US-20050158662-A1 Adamantane derivatives and resin compositions using the same as raw material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2005-07-21 US disclosed
US-20040210082-A1 Production method of adamantyl acrylate compounds MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-10-21 US disclosed
EP-1468981-A1 Production method of adamantyl acrylate compounds MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-10-20 EP disclosed
US-6632585-B1 Copolymer of partially deuterated and/or halogenated vinyl siloxanes; heat, water and chemical resistance; high transmission at communication wavelength ranges NIPPON SHEET GLASS CO., LTD. (JP) 2003-10-14 US disclosed
EP-1154323-A1 PHOTOSENSITIVE COMPOSITION, AND OPTICAL WAVEGUIDE ELEMENT AND PROCESS FOR PRODUCING THE SAME Nippon Sheet Glass Co., Ltd. (JP) 2001-11-14 EP disclosed
US-4001319-A FROM TRIFLUOROACETYL FLUORIDE AND SULFUR TRIOXIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040210082-A1 Production method of adamantyl acrylate compounds APEH, CYP51A1, NAAA MAPT 937/4885ALDH1A1 71/4885MEN1 1073/4885
US-20090053175-A1 SUBSTITUTE PYRROLIDINE DERIVATIVES POLRMT, EIF2AK2, NSUN2 MAPT 4463/4885ALDH1A1 442/4885MEN1 4827/4885
US-20090104136-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME TET1, TET2, TET3 MAPT 1213/4885ALDH1A1 457/4885MEN1 3094/4885
US-20160038388-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME TET1, TET2, TET3 MAPT 1213/4885ALDH1A1 457/4885MEN1 3094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.