Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.55 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18800052 | 0.89 | MTNR1A (0.64) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL18800026 | 0.87 | MTNR1A (0.51) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL18800042 | 0.86 | SPR (0.55) | MTNR1AMTNR1B | |
| SCHEMBL18800080 | 0.85 | MTNR1A (0.46) | MTNR1AMTNR1B | |
| SCHEMBL18800043 | 0.81 | MTNR1A (0.41) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL13286917 | 0.78 | PTGS2 (0.74) | — | |
| SCHEMBL18222517 | 0.77 | HTR6 (0.56) | MTNR1AMTNR1B | |
| SCHEMBL18800030 | 0.77 | MTNR1A (0.49) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL18800058 | 0.76 | MTNR1A (0.48) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL18800029 | 0.75 | MTNR1A (0.46) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637451-B2 | Indole compound | ASTELLAS PHARMA INC. (JP) | 2017-05-02 | — | — | US | disclosed |