Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18801108 | 0.90 | ALOX5 (0.48) | ALOX5MAPTMEN1KMT2AGRM6 | |
| SCHEMBL1650025 | 0.90 | ALOX5 (0.39) | ALOX5MAPTMEN1KMT2APOLB | |
| SCHEMBL1648072 | 0.88 | MAPT (0.47) | ALOX5MAPTMEN1KMT2AALOX15 | |
| SCHEMBL18801340 | 0.81 | MAPT (0.43) | ALOX5MAPTMEN1KMT2AALOX15 | |
| SCHEMBL1648422 | 0.81 | ALOX5 (0.52) | ALOX5MAPTMEN1KMT2AALOX15 | |
| SCHEMBL6844873 | 0.80 | ALOX5 (0.46) | ALOX5MAPTMEN1KMT2AALOX15 | |
| SCHEMBL1648902 | 0.79 | MAPT (0.45) | MAPTMEN1KMT2AALOX15USP2 | |
| SCHEMBL1648090 | 0.78 | MAPT (0.55) | MAPTMEN1KMT2AALOX15USP2 | |
| SCHEMBL1648194 | 0.77 | L3MBTL1 (0.46) | ALOX5MAPTMEN1KMT2ALMNA | |
| SCHEMBL1647924 | 0.77 | LMNA (0.47) | ALOX5MAPTMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486004-B1 | SULPHONE COMPOUNDS FOR USE IN THE TREATMENT OF OBESITY | ZAFGEN INC (US) | 2017-05-03 | — | — | EP | disclosed |