SCHEMBL18801151

SCHEMBL18801151

CC(C)(C)OC(O)c1c(CS(=O)(=O)c2ccccc2)ccc(-c2ccoc2)c1OCC#N

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NAT1 P18440 1/20 0.33
METAP2 P50579 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1648908 0.82 METAP2 (0.34) NAT1METAP2
SCHEMBL1648191 0.80 METAP2 (0.39) NAT1METAP2
SCHEMBL18784217 0.71 GBA1 (0.34) NAT1METAP2
SCHEMBL6844868 0.70 METAP2 (0.35) NAT1METAP2
SCHEMBL1648269 0.69 METAP2 (0.43) NAT1METAP2
SCHEMBL1647756 0.69 METAP2 (0.53) NAT1METAP2
SCHEMBL1648322 0.69 METAP2 (0.34) NAT1METAP2
SCHEMBL1648491 0.69 METAP2 (0.36) NAT1METAP2
SCHEMBL1648460 0.68 NAT1 (0.36) NAT1METAP2
SCHEMBL6844906 0.68 METAP2 (0.40) NAT1METAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2486004-B1 SULPHONE COMPOUNDS FOR USE IN THE TREATMENT OF OBESITY ZAFGEN INC (US) 2017-05-03 EP disclosed