Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18801417 | 0.82 | KMT2A (0.44) | KMT2ASLC37A4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18801282 | 0.81 | KMT2A (0.43) | KMT2ASLC37A4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18801137 | 0.80 | KMT2A (0.43) | KMT2ASLC37A4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18801059 | 0.79 | KMT2A (0.42) | KMT2ASLC37A4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1648275 | 0.77 | KMT2A (0.39) | KMT2AL3MBTL1CYP2D6ALDH1A1KDM4E | |
| SCHEMBL18801035 | 0.77 | KMT2A (0.43) | KMT2ASLC37A4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18801309 | 0.75 | CA12 (0.57) | KMT2ASLC37A4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18801293 | 0.73 | KMT2A (0.45) | KMT2ASLC37A4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28104576 | 0.72 | PPARG (0.48) | KMT2ANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL18801055 | 0.72 | SLC37A4 (0.38) | KMT2ASLC37A4NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486004-B1 | SULPHONE COMPOUNDS FOR USE IN THE TREATMENT OF OBESITY | ZAFGEN INC (US) | 2017-05-03 | — | — | EP | disclosed |