Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18801059 | 0.83 | KMT2A (0.42) | KMT2ASLC37A4RAB9ANPC1L3MBTL1 | |
| SCHEMBL1649341 | 0.81 | METAP2 (0.47) | KMT2AMETAP2SLC37A4RAB9ANPC1 | |
| SCHEMBL18801417 | 0.79 | KMT2A (0.44) | KMT2AMETAP2SLC37A4RAB9ANPC1 | |
| SCHEMBL1649016 | 0.79 | METAP2 (0.47) | KMT2AMETAP2L3MBTL1ALDH1A1TUBB4A | |
| SCHEMBL18801282 | 0.78 | KMT2A (0.43) | KMT2ASLC37A4RAB9ANPC1POLB | |
| SCHEMBL18801404 | 0.77 | KMT2A (0.38) | KMT2ASLC37A4RAB9ANPC1POLB | |
| SCHEMBL18801137 | 0.77 | KMT2A (0.43) | KMT2ASLC37A4RAB9ANPC1HPGD | |
| SCHEMBL18801055 | 0.76 | SLC37A4 (0.38) | KMT2ASLC37A4RAB9ANPC1L3MBTL1 | |
| SCHEMBL18801149 | 0.76 | L3MBTL1 (0.39) | KMT2ASLC37A4RAB9ANPC1POLB | |
| SCHEMBL18801286 | 0.75 | SLC37A4 (0.37) | KMT2ASLC37A4RAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486004-B1 | SULPHONE COMPOUNDS FOR USE IN THE TREATMENT OF OBESITY | ZAFGEN INC (US) | 2017-05-03 | — | — | EP | disclosed |