Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18801055 | 0.87 | SLC37A4 (0.38) | KMT2ASLC37A4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1649341 | 0.87 | METAP2 (0.47) | KMT2ASLC37A4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18801286 | 0.85 | SLC37A4 (0.37) | KMT2ASLC37A4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18801417 | 0.85 | KMT2A (0.44) | KMT2ASLC37A4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18801282 | 0.84 | KMT2A (0.43) | KMT2ASLC37A4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18801293 | 0.83 | KMT2A (0.45) | KMT2ASLC37A4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18801137 | 0.83 | KMT2A (0.43) | KMT2ASLC37A4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18801149 | 0.81 | L3MBTL1 (0.39) | KMT2ASLC37A4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18801404 | 0.81 | KMT2A (0.38) | KMT2ASLC37A4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18801035 | 0.80 | KMT2A (0.43) | KMT2ASLC37A4SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486004-B1 | SULPHONE COMPOUNDS FOR USE IN THE TREATMENT OF OBESITY | ZAFGEN INC (US) | 2017-05-03 | — | — | EP | disclosed |