Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20749354 | 0.94 | IDO1 (0.53) | IDO1LMNAMAOAMAOBHTR2A | |
| SCHEMBL20749180 | 0.92 | IDO1 (0.52) | IDO1LMNAMAOAMAOBSIGMAR1 | |
| SCHEMBL20131148 | 0.79 | IDO1 (0.55) | IDO1LMNAMAOASIGMAR1AOC3 | |
| SCHEMBL19880725 | 0.79 | IDO1 (0.55) | IDO1LMNAMAOAMAOBHTR2A | |
| SCHEMBL1520805 | 0.76 | IDO1 (1.00) | IDO1LMNAMAOAMAOBHTR2A | |
| SCHEMBL27940371 | 0.76 | IDO1 (0.61) | IDO1LMNAMAOAMAOBHTR2A | |
| SCHEMBL22029814 | 0.75 | IDO1 (0.67) | IDO1LMNAMAOAMAOBHTR2A | |
| SCHEMBL196951 | 0.75 | IDO1 (0.67) | IDO1LMNAMAOAHTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL1715614 | 0.74 | IDO1 (0.95) | IDO1LMNAMAOAMAOBHTR2A | |
| SCHEMBL19880682 | 0.73 | IDO1 (0.48) | IDO1LMNAMAOAMAOBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019027941-A1 | CARBAMOYL PHENYLALANINOL ANALOGS AND USES THEREOF | JAZZ PHARMACEUTICALS INTERNATIONAL III LIMITED (BM) | 2019-02-07 | — | — | WO | disclosed |
| EP-2861571-B1 | PHENYLALKYL SULFAMATE COMPOUND AND MUSCLE RELAXANT COMPOSITION COMPRISING THE SAME | BIO-PHARM SOLUTIONS CO LTD (KR) | 2017-05-03 | — | — | EP | disclosed |