Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19880682 | 0.94 | IDO1 (0.48) | IDO1LMNAALDH1A1HPGDALOX15 | |
| SCHEMBL19880675 | 0.92 | SIGMAR1 (0.47) | IDO1SIGMAR1MAOATDP1FFAR1 | |
| SCHEMBL19880687 | 0.87 | ALDH1A1 (0.48) | IDO1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL18802189 | 0.79 | IDO1 (0.61) | IDO1LMNASIGMAR1MAOAMEN1 | |
| SCHEMBL20131148 | 0.79 | IDO1 (0.55) | IDO1LMNASIGMAR1MAOADRD3 | |
| SCHEMBL21472357 | 0.78 | TSHR (0.54) | IDO1ALDH1A1TDP1SMN1; SMN2HRH3 | |
| SCHEMBL21471971 | 0.76 | TSHR (0.52) | IDO1LMNAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL20990572 | 0.76 | TSHR (0.52) | IDO1LMNAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL21472358 | 0.76 | TSHR (0.52) | IDO1LMNAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL18495415 | 0.76 | TSHR (0.52) | IDO1LMNAALDH1A1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9895454-B2 | Metal oxide catalyzed radiofluorination | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-02-20 | — | — | US | disclosed |
| US-20170224851-A1 | METAL OXIDE CATALYZED RADIOFLUORINATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170224851-A1 | METAL OXIDE CATALYZED RADIOFLUORINATION | TRHDE, TPO, TERT | IDO1 818/4885LMNA 3604/4885ALDH1A1 1513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.