Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19880675 | 0.98 | SIGMAR1 (0.47) | IDO1MAOAMAOBSIGMAR1FFAR1 | |
| SCHEMBL19880725 | 0.94 | IDO1 (0.55) | IDO1MAOAMAOBSIGMAR1FFAR1 | |
| SCHEMBL19880687 | 0.85 | ALDH1A1 (0.48) | IDO1MAOAMAOBALDH1A1HPGD | |
| SCHEMBL20749354 | 0.80 | IDO1 (0.53) | IDO1MAOAMAOBSIGMAR1FFAR1 | |
| SCHEMBL20749180 | 0.78 | IDO1 (0.52) | IDO1MAOAMAOBSIGMAR1L3MBTL1 | |
| SCHEMBL18458925 | 0.78 | L3MBTL1 (0.49) | IDO1MAOASIGMAR1L3MBTL1TDP1 | |
| SCHEMBL22784212 | 0.77 | IDO1 (0.54) | IDO1MAOAMAOBSIGMAR1FFAR1 | |
| SCHEMBL198056 | 0.76 | IDO1 (0.58) | IDO1MAOAMAOBSIGMAR1L3MBTL1 | |
| SCHEMBL21472357 | 0.76 | TSHR (0.54) | IDO1ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL451456 | 0.75 | MAOA (0.74) | IDO1MAOAMAOBSIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9895454-B2 | Metal oxide catalyzed radiofluorination | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-02-20 | — | — | US | disclosed |
| US-20170224851-A1 | METAL OXIDE CATALYZED RADIOFLUORINATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170224851-A1 | METAL OXIDE CATALYZED RADIOFLUORINATION | TRHDE, TPO, TERT | IDO1 818/4885MAOA 167/4885MAOB 203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.