Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18458925 | 0.92 | L3MBTL1 (0.49) | IDO1L3MBTL1SIGMAR1MAOA | |
| SCHEMBL8757293 | 0.87 | CA1 (0.44) | IDO1 | |
| SCHEMBL24041896 | 0.82 | HTR1A (0.49) | LMNAL3MBTL1HTR1A | |
| SCHEMBL24041827 | 0.81 | MAOA (0.46) | SIGMAR1MAOADRD3KCNH2 | |
| SCHEMBL18802189 | 0.79 | IDO1 (0.61) | IDO1LMNAMEN1KMT2ASIGMAR1 | |
| SCHEMBL19880725 | 0.79 | IDO1 (0.55) | IDO1LMNAMEN1KMT2ASIGMAR1 | |
| SCHEMBL20344725 | 0.79 | L3MBTL1 (0.51) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL24675563 | 0.77 | L3MBTL1 (0.54) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL90811 | 0.76 | IDO1 (0.61) | IDO1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL27518134 | 0.75 | IDO1 (0.55) | IDO1LMNASIGMAR1CHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3313840-B1 | HETEROARYL SUBSTITUTED AMINOPYRIDINE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2019-07-24 | — | — | EP | disclosed |
| US-20180127543-A1 | ORGANIC FLUORINE COMPOUND AND LUBRICANT | SHOWA DENKO K.K. (JP) | 2018-05-10 | — | — | US | disclosed |