Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2614365 | 0.88 | KDM4E (0.60) | KDM4ENPC1GAAHSD17B10L3MBTL1 | |
| SCHEMBL31612679 | 0.72 | KDM4E (0.55) | KDM4ENPC1GAAHSD17B10L3MBTL1 | |
| SCHEMBL29410608 | 0.72 | DNMT1 (0.59) | KDM4EGAAHSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL196007 | 0.72 | DNMT1 (0.59) | KDM4EGAAHSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL29787010 | 0.72 | DNMT1 (0.59) | KDM4EGAAHSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL2614354 | 0.72 | NPC1 (0.64) | KDM4ENPC1GAAHSD17B10L3MBTL1 | |
| SCHEMBL3676506 | 0.72 | ALDH1A1 (0.47) | KDM4EHSD17B10L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL19374774 | 0.71 | NPC1 (0.68) | KDM4ENPC1GAAHSD17B10L3MBTL1 | |
| SCHEMBL1752965 | 0.71 | KDM4E (0.44) | KDM4EGAAL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL18027880 | 0.70 | L3MBTL1 (0.59) | KDM4ENPC1GAAHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676693-B2 | Bulky ligands and metal compounds comprising bulky ligands | MARSHAK MICHAEL PESEK (US) | 2017-06-13 | — | — | US | disclosed |
| US-9676693-B2 | Bulky ligands and metal compounds comprising bulky ligands | MARSHAK MICHAEL PESEK (US) | 2017-06-13 | — | — | US | disclosed |
| US-20170121263-A1 | BULKY LIGANDS AND METAL COMPOUNDS COMPRISING BULKY LIGANDS | MARSHAK MICHAEL PESEK (US) | 2017-05-04 | — | — | US | disclosed |
| US-20170121263-A1 | BULKY LIGANDS AND METAL COMPOUNDS COMPRISING BULKY LIGANDS | MARSHAK MICHAEL PESEK (US) | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121263-A1 | BULKY LIGANDS AND METAL COMPOUNDS COMPRISING BULKY LIGANDS | ACACB, ACACA, ZKSCAN2 | KDM4E 2054/4885NPC1 1588/4885GAA 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.