SCHEMBL188044

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10554350	0.89	ALDH1A1 (0.47)	ALDH1A1POLBMAPTL3MBTL1HTT
	SCHEMBL5169785	0.89	HRH3 (0.46)	ALDH1A1HRH3HTTATMMEN1
	SCHEMBL22031681	0.89	HRH3 (0.39)	ALDH1A1POLBHRH3CYP2D6
	SCHEMBL7723416	0.89	ALDH1A1 (0.35)	ALDH1A1POLBHRH3MAPTHPGD
	SCHEMBL3164216	0.89	ALDH1A1 (0.52)	ALDH1A1POLBHRH3MAPTHPGD
	SCHEMBL4750348	0.89	HRH3 (0.46)	ALDH1A1POLBHRH3MAPTHPGD
	SCHEMBL443667	0.89	HRH3 (0.45)	ALDH1A1HRH3MAPTHPGDMEN1
	SCHEMBL74752	0.87	CYP2D6 (0.41)	ALDH1A1HRH3HPGDMEN1KMT2A
	SCHEMBL28643916	0.87	CYP2D6 (0.41)	ALDH1A1HRH3HPGDMEN1KMT2A
	SCHEMBL1456783	0.87	CYP2D6 (0.41)	ALDH1A1HRH3HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.